100 Recruiting Studies Using Psilocybin
Active clinical trials that use this intervention, sourced directly from the NIH registry.
Browse by conditionTrials Using Psilocybin
Observational Pilot Study to Explore the Social and Health Impacts of a New Model of Care in Oregon: Psilocybin Services on Alcoholism
📍 Innertrek Patient Service Center — Portland, Oregon
Alcohol Use Disorder
View Study & Checklist ➔Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Patients With Advanced Cancer
📍 Princess Margaret Cancer Centre — Toronto, Ontario
Advanced Cancer
View Study & Checklist ➔Feasibility, Clinical Effects, and Safety of Psilocybin-assisted Psychotherapy for Treatment-resistant OCD
📍 Centre for Addiction and Mental Health — Toronto, Ontario
Obsessive-Compulsive Disorder
View Study & Checklist ➔Psilocybin-Assisted vs Ketamine-Assisted Psychotherapy for Alcohol Use Disorder
📍 University of Iowa — Iowa City, Iowa
Alcohol Use Disorder
View Study & Checklist ➔Psilocybin for Major Depressive Disorder (MDD)
📍 University of Alabama Clinical Research Unit — Birmingham, Alabama
Depressive Disorder, Major
View Study & Checklist ➔A Study of Psilocybin for PTSD
📍 Johns Hopkins Center for Psychedelic and Consciousness Research — Baltimore, Maryland
Post Traumatic Stress Disorder
View Study & Checklist ➔Effects of Psilocybin in Obsessive Compulsive Disorder
📍 Johns Hopkins University School of Medicine — Baltimore, Maryland
Obsessive-Compulsive Disorder
View Study & Checklist ➔An Open Label Study of the Safety and Efficacy of Psilocybin in Participants With Treatment-Resistant Depression (P-TRD)
📍 VA Palo Alto Healthcare System/Stanford Medicine — Palo Alto, California
Treatment Resistant Depression
View Study & Checklist ➔Neurobiological Effects of Psilocybin in Treatment Resistant Bipolar Depression
📍 Toronto Western Hospital - University Health Network — Toronto, Ontario
Bipolar Depression
View Study & Checklist ➔Psilocybin Therapy for Chronic Low Back Pain
📍 University of California San Francisco — San Francisco, California
Chronic Low-back Pain
View Study & Checklist ➔Psilocybin Treatment of Major Depressive Disorder With Co-occurring Alcohol Use Disorder
📍 Johns Hopkins Center for Psychedelic and Consciousness Research — Baltimore, Maryland
Major Depressive Disorder
View Study & Checklist ➔Pilot Trial of Visual Healing® in Psilocybin-assisted Therapy for Alcohol Use Disorder
📍 Pacific Treatment & Research in Psychedelics — Santa Monica, California
Alcohol Use Disorder
View Study & Checklist ➔Two Doses of Psilocybin for the Treatment of MDD in Adults With Cancer
📍 Sunstone Medical, PC — Rockville, Maryland
Cancer
View Study & Checklist ➔PSilocybin for psYCHological and Existential Distress in PALliative Care (PSYCHED-PAL)
📍 The Ottawa Hospital — Ottawa, Ontario
Depression, Anxiety
View Study & Checklist ➔PsiloStudy: Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PTSD & Alcohol Use Disorder (AUD)
📍 University of Washington Center for Novel Therapeutics in Addiction Psychiatry — Seattle, Washington
Alcohol Use Disorder (AUD)
View Study & Checklist ➔Does Psilocybin Change Synaptic Density in Amnestic Mild Cognitive Impairment
📍 Centre for Addiction and Mental Health — Toronto, Ontario
Amnestic Mild Cognitive Impairment
View Study & Checklist ➔A Phase II, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of COMP360 in Participants With Recurrent Major Depressive Disorder
📍 Kadima Neuropsychiatry Institute — La Jolla, California
Major Depressive Disorder
View Study & Checklist ➔Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD
📍 Lighthouse Psychiatry Scottsdale — Gilbert, Arizona
Treatment Resistant Depression
View Study & Checklist ➔Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or Incurable Hematologic Malignancies
📍 Fred Hutch/University of Washington Cancer Consortium — Seattle, Washington
Anxiety
View Study & Checklist ➔Comparing the Effects of Psilocin and Psilocybin in Healthy Adults
📍 University of California, San Francisco — San Francisco, California
Healthy
View Study & Checklist ➔Psilocybin for the Treatment of Veterans With Post-Traumatic Stress Disorder
📍 Ohio State University Department of Psychiatry and Behavioral Health at the Davis Medical Research Center — Columbus, Ohio
PTSD
View Study & Checklist ➔Neural and Physiological Correlates of Psychedelic Sub-states
📍 University of California, San Francisco — San Francisco, California
Psychedelic Experiences
View Study & Checklist ➔Psilocybin-Assisted Therapy in Treatment-Resistant Depression
📍 UNC Chapel Hill Medical Center — Chapel Hill, North Carolina
Refractory Depression
View Study & Checklist ➔Psilocybin in the Treatment of Cannabis Use Disorder: A-Proof-of-Concept Study
📍 MacAnxiety Research Centre — Hamilton, Ontario
Cannabis Use Disorder, Moderate
View Study & Checklist ➔Effects of Repeated Psilocybin Dosing in OCD
📍 Enact Research Collaborative (40 Temple St, 4th Floor) — New Haven, Connecticut
Obsessive-Compulsive Disorder
View Study & Checklist ➔Psilocybin-Enhanced Psychotherapy for Methamphetamine Use Disorder
📍 Portland VA Health Care System — Vancouver, Washington
Amphetamine-Related Disorders
View Study & Checklist ➔Psilocybin for Treatment-Resistant Depression in Autism
📍 Centre for Addiction and Mental Health — Toronto, Ontario
Treatment Resistant Depression
View Study & Checklist ➔Psilocybin Therapy for Depression in Bipolar II Disorder
📍 University of California, San Francisco — San Francisco, California
Bipolar II Disorder
View Study & Checklist ➔Psilocybin Effects on Healthy Aging Biomarkers and Purpose in Life
📍 Vail Health Behavioral Health — Edwards, Colorado
Aging
View Study & Checklist ➔The Effects of Psilocybin on Social Connectedness
📍 Connecticut Mental Health Center — New Haven, Connecticut
Loneliness
View Study & Checklist ➔Understanding Music and Mindfulness Preferences in Psilocybin-Assisted Psychotherapy
📍 Jewish General Hospital — Montreal, Quebec
Treatment-Resistant Major Depressive Disorder
View Study & Checklist ➔Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain
📍 Connecticut Mental Health Center — New Haven, Connecticut
Chronic Low Back Pain (CLBP)
View Study & Checklist ➔Psilocybin for Chronic Pelvic Pain (CPP) in Women: A Pilot Feasibility Study
📍 Oregon Health & Science University — Portland, Oregon
Chronic Pelvic Pain
View Study & Checklist ➔Psilocybin After Trauma Surgery for Pain
📍 UPMC Presbyterian — Pittsburgh, Pennsylvania
Pain Management
View Study & Checklist ➔Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder
📍 Goodman Hall, Dept of Psychiatry, Indiana University — Indianapolis, Indiana
Treatment Resistant Depression
View Study & Checklist ➔Group PACBT for Depression
📍 UCLA Semel Institute — Los Angeles, California
Depression - Major Depressive Disorder
View Study & Checklist ➔Consciousness and Psilocybin Effects on Well-Being: The CoPEWell Study
📍 University of Wisconsin — Madison, Wisconsin
Well-Being, Psychological
View Study & Checklist ➔The Acute Effects of Psilocybin on Cognition, Memory, and Brain Function
📍 The University of Texas at Austin Dell Medical School — Austin, Texas
Healthy
View Study & Checklist ➔Psilocybin-Assisted Psychotherapy in Treating Irritable Bowel Syndrome (IBS)
📍 NYU Langone Health — New York, New York
IBS - Irritable Bowel Syndrome
View Study & Checklist ➔NeuroGuard: Psilocybin Trial for Preventing Chemo-induced Neuropathy
📍 MD Anderson Cancer Center — Houston, Texas
Psilocybin
View Study & Checklist ➔Psilocybin-Assisted Therapy as a Treatment for Depression
📍 Washington University School of Medicine — St Louis, Missouri
Depression
View Study & Checklist ➔Psilocybin-Assisted Therapy for Treatment-Resistant Depression in Bipolar II Disorder
📍 Djavad Mowafaghian Centre for Brain Health — Vancouver, British Columbia
Bipolar II Depression
View Study & Checklist ➔Psilocybin-Assisted Therapy
📍 Emory University Hospital — Atlanta, Georgia
PTSD
View Study & Checklist ➔Neuroplasticity Enhancement From Cognitive Training Reinforced by Psilocybin
📍 National Institute of Aging, Clinical Research Unit — Baltimore, Maryland
Alzheimer's Disease
View Study & Checklist ➔Psilocybin as a Novel Therapy for Residual Anhedonia
📍 NYU Langone Health — New York, New York
Anhedonia
View Study & Checklist ➔Psilocybin-assisted Therapy for Comorbid Major Depressive Disorder and Alcohol Use Disorder
📍 Centre for Addiction and Mental Health — Toronto, Ontario
Major Depressive Disorder (MDD)
View Study & Checklist ➔Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder
📍 Brigham and Women's Hospital — Boston, Massachusetts
Alcohol Use Disorder
View Study & Checklist ➔Psilocybin-assisted Therapy for Post-Traumatic Stress Disorder in Survivors of Intimate Partner Violence
📍 University of Calgary — Calgary, Alberta
Post Traumatic Stress Disorder PTSD
View Study & Checklist ➔Psilocybin Therapy for Methamphetamine Use Disorder and HIV
📍 UCSF at Zuckerberg San Francisco General Hospital — San Francisco, California
Methamphetamine Use Disorder
View Study & Checklist ➔Effects of Psilocybin on Speech Fluency, Struggle, and Brain Activity in People Who Stutter
📍 NYU Langone Health — New York, New York
Stuttering
View Study & Checklist ➔Study of Psilocybin Under Anesthesia Controlled by EEG
📍 Stanford University — Stanford, California
Major Depression
View Study & Checklist ➔Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids
📍 Roswell Park Cancer Institute — Buffalo, New York
Hematopoietic and Lymphatic System Neoplasm
View Study & Checklist ➔Psilocybin for Methamphetamine Use Disorder
📍 University of Alabama at Birmingham — Birmingham, Alabama
Methamphetamine Use Disorder
View Study & Checklist ➔Investigating the Mechanisms of the Effects of Psilocybin on Visual Perception and Visual Representations in the Brain
📍 University of California, Berkeley — Berkeley, California
Perception Disorders
View Study & Checklist ➔Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)
📍 Yale University — New Haven, Connecticut
Opioid Use Disorder
View Study & Checklist ➔Psilocybin Administration With 5-HT1a Blockade
📍 Center for Psychedelics and Consciousness Research — Baltimore, Maryland
Psychedelic Effects in Healthy Volunteers
View Study & Checklist ➔Psilocybin-Assisted Cognitive Processing Therapy for Chronic PTSD
📍 St. Michael's Hospital, Unity Health Toronto — Toronto, Ontario
Post Traumatic Stress Disorder
View Study & Checklist ➔Psilocybin and Methylenedioxymethamphetamine (MDMA) for Post-traumatic Stress Disorder (PTSD)
📍 Johns Hopkins Center for Psychedelic and Consciousness Research — Baltimore, Maryland
Posttraumatic Stress Disorder
View Study & Checklist ➔Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD
📍 Sunstone Medical, PC — Rockville, Maryland
Post Traumatic Stress Disorder
View Study & Checklist ➔Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung Cancer
📍 Ohio State University Comprehensive Cancer Center — Columbus, Ohio
Lung Non-Small Cell Carcinoma
View Study & Checklist ➔5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder
📍 University of Alabama at Birmingham — Birmingham, Alabama
Tobacco Use Disorder
View Study & Checklist ➔State-Funded Trial Assessing Recovery and Long-Term Impact of Guided Psilocybin for Healing Trauma
📍 Baylor College of Medicine — Houston, Texas
PTSD
View Study & Checklist ➔Psilocybin-Assisted Psychotherapy for Alcohol Use Disorder
📍 University of Calgary — Calgary, Alberta
Alcohol Use Disorder
View Study & Checklist ➔Pragmatic Trial of Psilocybin Therapy in Palliative Care
📍 Marin Cancer Care — Greenbrae, California
Demoralization
View Study & Checklist ➔Psilocybin as a Treatment for Chronic Pain in Smokers
📍 Department of Veterans Affairs — West Haven, Connecticut
Smokers With Chronic Pain
View Study & Checklist ➔Psilocybin for Enhanced Analgesia in Chronic nEuropathic PAIN
📍 St. Michael's Hospital. Unity Health Toronto — Toronto, Ontario
Chronic Neuropathic Pain
View Study & Checklist ➔Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and Suicidality
📍 The University of Texas Health Science Center at Houston — Houston, Texas
Bipolar II Disorder
View Study & Checklist ➔Effects of Psilocybin in Patients With Amyotrophic Lateral Sclerosis
📍 Johns Hopkins Center for Psychedelic and Consciousness Research — Baltimore, Maryland
Amyotrophic Lateral Sclerosis
View Study & Checklist ➔Mindfulness-Assisted Psychedelic Therapy
📍 Univeristy of Southern California Brain and Creativity Institute — Los Angeles, California
Mental Health
View Study & Checklist ➔Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability
📍 Johns Hopkins — Baltimore, Maryland
Stroke
View Study & Checklist ➔Psilocybin With Pimavanserin Compared to Psilocybin Alone for the Treatment of Major Depressive Disorder
📍 Icahn School of Medicine at Mount Sinai, Center for Psychedelic Therapy Research — New York, New York
Major Depressive Disorder
View Study & Checklist ➔Open-Label Psilocybin Study in Transdiagnostic Population
📍 Connecticut Mental Health Center - Yale School of Medicine — New Haven, Connecticut
Transdiagnostic
View Study & Checklist ➔Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication
📍 University of British Columbia - Okanagan Campus — Kelowna, British Columbia
Opioid Dependence
View Study & Checklist ➔Mindfulness-based Psilocybin Therapy for PTSD
📍 The Ohio State University Medical Center — Columbus, Ohio
Post Traumatic Stress Disorder
View Study & Checklist ➔Investigation to Understand and Optimize Psilocybin
📍 Vail Health Behavioral Health — Edwards, Colorado
Depression
View Study & Checklist ➔Psilocybin for Methamphetamine Addiction
📍 LSU Health Shreveport — Shreveport, Louisiana
Methamphetamine Use Disorder
View Study & Checklist ➔Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression
📍 Birmingham VA Medical Center, Birmingham, AL — Birmingham, Alabama
Major Depression
View Study & Checklist ➔Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD
📍 NYU Langone Health — New York, New York
Alcohol Use Disorder
View Study & Checklist ➔Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND)
📍 Centre for Addiction and Mental Health — Toronto, Ontario
Treatment Resistant Depression
View Study & Checklist ➔Psilocybin rTMS for Treatment Resistant Depression
📍 Health Discovery Building (HDB), 1601 Trinity St., Bldg B., Z0600 — Austin, Texas
Treatment Resistant Depression
View Study & Checklist ➔Psilocybin in Chronic Low Back Pain and Depression
📍 Johns Hopkins University School of Medicine — Baltimore, Maryland
Chronic Low-back Pain
View Study & Checklist ➔Psilocybin in Cancer Pain Study
📍 Dana-Farber Cancer Institute — Boston, Massachusetts
Opioid-Related Disorders
View Study & Checklist ➔Psilocybin for Prolonged Grief Disorder
📍 University of Virginia — Charlottesville, Virginia
Prolonged Grief Disorder
View Study & Checklist ➔Psilocybin to Treat Depression in Spinal Cord Injury
📍 James J. Peters Department of Veterans Affairs Medical Center — The Bronx, New York
Spinal Cord Injury
View Study & Checklist ➔Safety and Tolerability Trial of Psilocybin in Healthy Older Adults
📍 University of California San Francisco (UCSF) Department of Neurology — San Francisco, California
Healthy Volunteer
View Study & Checklist ➔Safety, Tolerability, and Preliminary Efficacy of Psilocybin Oral Solution in Adults With Generalized Anxiety Disorder
📍 Kingston General Health Research Institute — Kingston, Ontario
Generalized Anxiety Disorder (GAD)
View Study & Checklist ➔Psilocybin Microdose for Psychological and Existential Distress in Palliative Care (PSYCHED-PAL-RCT)
📍 William Osler Health System — Brampton, Ontario
Psychological Distress
View Study & Checklist ➔TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors
📍 The University of Texas M. D. Anderson Cancer Center — Houston, Texas
Depression
View Study & Checklist ➔Subjective Experience Following Psilocybin
📍 University of Calgary — Calgary, Alberta
Investigating the Importance of the Subjective Psychedelic Experience
View Study & Checklist ➔The RECAP2 Study: Midazolam and Psilocybin
📍 UW School of Medicine and Public Health — Madison, Wisconsin
Psilocybin
View Study & Checklist ➔Study of Psilocybin Assisted Psychotherapy to Address Fear of Recurrence
📍 Outpatient CTRC — Aurora, Colorado
Breast Cancer
View Study & Checklist ➔Psilocybin-Assisted Therapy for Intergenerational Trauma
📍 The Parsons Research Center for Psychedelic Healing — New York, New York
Psychological Stress
View Study & Checklist ➔Evaluating the Role of Psilocybin Monitors in Psilocybin Therapy for Treatment Resistant Depression
📍 Toronto Western Hospital (University Health Network) — Toronto, Ontario
Treatment-Resistant Depression
View Study & Checklist ➔The ENHANCE Study: taVNS and Psilocybin
📍 University of Wisconsin - Madison — Madison, Wisconsin
Healthy
View Study & Checklist ➔Safety and Efficacy of Psilocybin-assisted Psychotherapy for Demoralization Syndrome in Patients Diagnosed With Advanced Stage Cancer
📍 Queen's University — Kingston, Ontario
Demoralization
View Study & Checklist ➔Wellcome Leap Psilocybin for OUD
📍 University of Pennsylvania — Philadelphia, Pennsylvania
Opioid Use Disorder
View Study & Checklist ➔Psilocybin for Opioid Use Disorder (OUD)
📍 Duke City Recovery Toolbox — Albuquerque, New Mexico
Opioid Use Disorder
View Study & Checklist ➔Psilocybin Efficacy With or Without Pimavanserin Pretreatment
📍 Johns Hopkins Center for Psychedelic and Consciousness Research — Baltimore, Maryland
Mood (Psychological Function)
View Study & Checklist ➔Psilocybin Therapy in Advanced Cancer
📍 University of Colorado Anschutz Medical campus (CU AMC) — Aurora, Colorado
Advanced Cancer
View Study & Checklist ➔Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Caregivers of Patients With Advanced Cancer
📍 Toronto General Hospital — Toronto, Ontario
Caregiver Distress
View Study & Checklist ➔