17 Paid Clinical Research Studies in Boulder, Colorado

A Comparison of ACL Repair With BEAR Device vs. Autograft Patellar Tendon ACL Reconstruction

This study is designed to evaluate bridge-enhanced ACL restoration (BEAR), a new surgical technique for repairing knees injured by a tear of the anterior cruciate ligament (ACL) th

📍 University of Colorado — Boulder, Colorado

💵 Approximately 100 patients will receive each of the experimental BEAR surgery and the comparative control BPTB reconstru

Fisetin to Improve Vascular Function in Older Adults

This is a pilot clinical trial to test the efficacy of intermittent treatment with the flavonoid compound fisetin for improving vascular endothelial function and reducing aortic st

📍 University of Colorado Boulder — Boulder, Colorado

Neural Substrates Underlying Adaptations in Manual Dexterity of Older Adults

Age-related declines in motor function can compromise independence and quality of life. This project examines how practice and somatosensory stimulation reshape the neural control

📍 University of Colorado Boulder — Boulder, Colorado

Biomarkers for Peripheral Circadian Clocks in Humans

The purpose of this project is to improve our understanding of peripheral circadian rhythms in humans. Circadian clocks are present in most tissues of the body with importance for

📍 Sleep and Chronobiology Laboratory — Boulder, Colorado

Health Ahead Comparative Effectiveness Study

The Health Ahead Comparative Effectiveness Study is a pragmatic, parallel-arm interventional platform that systematically compares successive changes to preventive health screening

📍 Longevity Metrics — Boulder, Colorado

Cannabis Observations on Brain Waves, Retrieval, and Attention: Experiment 4

This study investigates the impact of ∆9-tetrahydrocannabinol (THC) and cannabidiol (CBD) on recognition memory in healthy, regular cannabis users. Participants complete the same r

📍 Center for Innovation and Creativity (CINC) — Boulder, Colorado

Adipocyte-Derived Extracellular Vesicles, Weight Loss, and Endothelial Function

Changes in adipose tissue biology are now recognized as a key factor underlying the increased risk of metabolic and cardiovascular disease with obesity. Clinical interest in adipoc

📍 University of Colorado Boulder Clinical and Translational Research Center (CTRC) — Boulder, Colorado

Perceptual Influences From Smoking Cannabis: an Experimental Study

The purpose of the study is to better understand the effects of cannabis in relation to mental and physical states including its relationship with mood, cognition, perception inclu

📍 University of Colorado at Boulder — Boulder, Colorado

Human Observatory Study

The Human Observatory Study is a prospective observational and ecological surveillance study building a continuously-updating world model for human health, disease, and death at th

📍 Longevity Metrics — Boulder, Colorado

Nicotinamide Riboside for Treating Elevated Systolic Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults

Aging is the primary risk factor for cardiovascular diseases (CVD), the number one cause of death in developed societies. Systolic blood pressure (SBP) increase with age and is a k

📍 Integrative Physiology of Aging Laboratory — Boulder, Colorado

Longitudinal Outpatient Treatment for Cannabis Use Disorder

This study is a placebo-controlled randomized trial comparing the effects of hemp-derived cannabidiol (CBD) with and without Delta-9-tetrahydrocannabinol (THC), relative to placebo

📍 University of Colorado Boulder — Boulder, Colorado

💵 All participants will receive a five-session empirically supported psychological intervention to support cannabis use re

100-Year Human Aging Study

The 100-Year Human Aging Study is a prospective, pragmatic, observational trial enrolling participants across fixed and mobile clinical sites to undergo comprehensive multi-system

📍 Longevity Metrics — Boulder, Colorado

Passive Heat Therapy for Lowering Systolic Blood Pressure and Improving Vascular Function in Mid-life and Older Adults

This study aims to determine the effects of \~12 weeks of repeated hot water immersion ("heat therapy") vs. thermoneutral water immersion on blood pressure and vascular function in

📍 University of Colorado Boulder — Boulder, Colorado

Pathophysiology of Circadian Rhythm Delayed Sleep Wake Phase Disorder

The goal of this study is to understand factors that contribute to delayed sleep wake phase disorder (DSWPD). The investigators will examine whether patients with DSWPD exhibit alt

📍 University of Colorado — Boulder, Colorado

Inspiratory Muscle Strength Training for Lowering Blood Pressure and Improving Endothelial Function in Postmenopausal Women: Comparison With "Standard of Care" Aerobic Exercise

High blood pressure (BP) is the major modifiable risk factor for cardiovascular diseases (CVD) and related health conditions, particularly among postmenopausal (PM) women. In adult

📍 Integrative Physiology of Aging Laboratory — Boulder, Colorado

💵 Subjects will receive verbal and written instructions of the training protocol (5 sets of 6 breaths, 1 minute rest betwe

Evaluation of SUMMIT BRUSH in Treatment of Blepharitis

Dry Eye Disease (DED) is a multifactorial disease that affects \~15-30 million people in the USA alone. It creates an enormous societal and economic burden, decreases productivity

📍 University of Colorado — Boulder, Colorado

Studies of Human Inference Using On-line Testing

The investigators will record behavioral responses from human participants on crowdsourcing platform Prolific to identify the decision strategies humans apply short-term, long-term

📍 University of Colorado Boulder — Boulder, Colorado