20 Paid Clinical Research Studies in Hartford, Connecticut

Abemaciclib (LY2835219) in Patients With Recurrent Primary Brain Tumors

The purpose of this study is to test any good and bad effects of a study drug called abemaciclib (LY2835219) in patients with recurrent brain tumors.

📍 Hartford Healthcare Cancer Institute @ Hartford Hospital (Data collection only) — Hartford, Connecticut

💵 Patients may receive erythrocyte transfusions to achieve this hemoglobin level at the discretion of the investigator.

Major De-escalation to 30 Gy for Select Human Papillomavirus Associated Oropharyngeal Carcinoma

The purpose of this study is to demonstrate that participants with HPV positive and hypoxia negative T1-2, N1-2c (AJCC, 7th ed.) oropharyngeal squamous cell carcinoma receiving a m

📍 Hartford Healthcare (Data Collection) — Hartford, Connecticut

💵 If this baseline scan shows no evidence of hypoxia, the subject will receive 30Gy concurrent with 2 cycles of chemothera

Development of a Provider-Focused Intervention to Improve Health Outcomes in Pediatric Sickle Cell Disease

The goal of this interventional study is to learn about the impact of an intervention for health care providers that teaches individuation and perspective-taking (IPT) skills to en

📍 Connecticut Children's Medical Center — Hartford, Connecticut

Pelvic Floor Disorder Symptoms in Women Seeking Weight Loss Therapy

The purpose of this study is to compare change in pelvic floor symptoms between patients receiving medical therapy for weight loss and surgical treatment for weight loss. Examples

📍 Hartford Hospital — Hartford, Connecticut

Psilocybin Microdosing on Cognition, Mood and Quality of Life

This study is being conducted to evaluate how of 30 days of intermittently microdosed psilocybin affects mood, cognition, subjective well-being and structural/functional MRI result

📍 Olin Neuropsychiatry Research Center — Hartford, Connecticut

Army-SPRING Army-Suicide Prevention Research

Every unit in the Connecticut Army National Guard has a Suicide Intervention Officer to provide suicide intervention education awareness for their unit, monitor for soldiers in cri

📍 Connecticut Army National Guard — Hartford, Connecticut

Social Isolation and Aging in Schizophrenia

Individuals diagnosed with schizophrenia and related psychotic disorders (SZ) exhibit a markedly elevated risk of premature mortality, with a 10-20-year shorter lifespan relative t

📍 Olin Neuropsychiatry Research Center, Hartfort — Hartford, Connecticut

OSA-18 in Children With Mild Obstructive Sleep Apnea: Can it be a Helpful Decision Making Tool?

The concept is a novel research idea that incorporates the potential impact of patient quality of life (QOL) on decision-making for treatment of mild obstructive sleep apnea (OSA).

📍 Connecticut Children's Medical Center — Hartford, Connecticut

PRESERVE & CONNECT: Impact Study of the BPC

The PRESERVE \& CONNECT project is a multi-site randomized control trial of the Breakthrough Parenting Curriculum: Navigating Trauma Across Generations (BPC) in rural and racially

📍 University of Connecticut — Hartford, Connecticut

Integrative Training Program for Pediatric Sickle Cell Pain

This research aims to answer the question: does a group training program specifically for teens with chronic sickle cell disease (SCD) pain that teaches skills to strengthen the mi

📍 Connecticut Children's Medical Center — Hartford, Connecticut

💵 In addition to usual care, participants will receive the I-STRONG intervention, which consists of 16 group-based telehea

Multifidus Cervicis Plane Block Vs. Sham Block For Posterior Cervical Spine Fusion Surgery

The goal of this randomized, double-blinded, clinical trial is to assess the benefit of administering a Multifidus Cervicis Plane (MCP) block compared to a sham block as a method o

📍 Hartford Hospital — Hartford, Connecticut

💵 Participants will receive preoperative bilateral MCP blocks on the back of their neck using the standard of care local a

Functional Neuroimaging of Alcoholism Vulnerability: Probing Glutamate and Reward, Using the mGluR5 Inhibitor Mavoglurant

The purpose of this study is to evaluate the role of Mavoglurant in clarifying the neurobiology of alcoholism risk. This is a one-site, randomized, within subjects, counterbalanced

📍 Hartford Hospital — Hartford, Connecticut

💵 cancer, heart failure) * Current pregnancy (all females will be tested with urine screens on the day of MRI) * Women not

Target ADHD Executive Working Memory Replication Study

The proposed study will replicate target engagement as assessed in the first phase while also determining if it correlates with clinically meaningful improvements in ADHD dysfuncti

📍 Institute of Living/Hartford Hospital — Hartford, Connecticut

Easing Scan Anxiety in Pediatric Oncology Caregivers Through Meditation-based Programs

"Scanxiety" is a term coined to describe anxiety related to imaging during cancer treatment and has not been robustly studied in pediatric oncology caregivers. Mindfulness-based St

📍 Connecticut Children's Medical Center — Hartford, Connecticut

Liposomal Bupivacaine/Bupivacaine in Rectus Sheath Blocks Versus Ropivacaine in Rectus Sheath Blocks And Catheters

The goal of this pilot study is to compare single shot rectus sheath blocks of liposomal bupivacaine/bupivacaine mixture to bilateral rectus sheath catheters infused with ropivacai

📍 Hartford Hospital — Hartford, Connecticut

💵 Participants will receive either a single dose of liposomal bupivacaine/bupivacaine mixture intraoperatively at the end

Strengthening the Connections to Opportunities for Prevention Engagement

The Strengthening the Connections to Opportunities for Prevention Engagement (SCOPE) project will create a pathway for children and families from the City of Hartford to connect wi

📍 Connecticut Children's — Hartford, Connecticut

Effects of Oral Tranexamic Acid Following Total Knee Arthroplasty

The primary purpose of this study is to evaluate postoperative pain. Secondary outcomes evaluated in this study will include range of motion (ROM), opioid consumption, and ambulati

📍 Trinity Health Of New England/CT Joint Replacement Institute — Hartford, Connecticut

💵 * History of stent placed within one year of surgery - patient will receive topical TXA as an alternative.

Modulating Temporoparietal Junction Mentalizing-Related Activity in Autism Spectrum Disorder (ASD) Using Transcranial Magnetic Stimulation (TMS)

The goal of this observational study is to test the modulation effect of different transcranial magnetic stimulation (TMS) on the neural network supporting our ability to create me

📍 Olin Neuropsychiatry Research Center (ONRC) — Hartford, Connecticut

Cryocompression to Reduce Chemotherapy-induced Peripheral Neuropathy in Gynecologic Cancer - COHORT 2

The investigators aim to determine the effect of cryotherapy wraps plus compression therapy (henceforth referred to as cryocompression) versus cryotherapy wraps alone on the incide

📍 Hartford Healthcare Cancer Institute — Hartford, Connecticut

💵 Participants will receive cryotherapy (+/- compression) for the duration of their taxane infusions.

Assessment and Educational Intervention to Reduce Ultra-processed Food Consumption in Pediatric Patients With IBD

This study explores whether simple nutrition education can help children and teens with inflammatory bowel disease (IBD) eat fewer ultra-processed foods (UPFs). UPFs include packag

📍 Connecticut Children's Medical Center — Hartford, Connecticut