21 Paid Clinical Research Studies in West Haven, Connecticut

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study I

The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.

📍 Biological Studies Unit, VA Connecticut Healthcare System — West Haven, Connecticut

Cannabinoids, Learning, and Memory

The overarching goal of this study is to characterize the effects of cannabinoids on working and episodic memory.

📍 VA Connecticut Healthcare System — West Haven, Connecticut

Fixed Order, Open-Label, Dose-Escalation Study of DMT in Humans

The goal of this fixed order, open-label, dose-escalation study is to investigate the safety and efficacy of specific doses of dimethyltryptamine (DMT) in humans.

📍 Biological Studies Unit at the VA Connecticut Healthcare System, Yale School of Medicine — West Haven, Connecticut

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition

The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.

📍 Biological Studies Unit, VA Connecticut Healthcare System — West Haven, Connecticut

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Substudy III

The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.

📍 Biological Studies Unit, VA Connecticut Healthcare System — West Haven, Connecticut

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study II

The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.

📍 Biological Studies Unit, VA Connecticut Healthcare System — West Haven, Connecticut

Probing the Cannabinoid System in Individuals With a Family History of Psychosis

The overall purpose of this study is to determine whether a family history of psychosis is associated with an altered cannabinoid system. This will be tested by studying individual

📍 VA Connecticut Healthcare System — West Haven, Connecticut

Development of a Mobile Health Intervention to Support Functioning of Veterans With Substance Use Disorders

This project will involve the development, refinement, and preliminary testing of a mobile health intervention (Motivational Enhancement Therapy Skills for Veterans; "METS4Vets"),

📍 VA Connecticut Healthcare System West Haven Campus, West Haven, CT — West Haven, Connecticut

Retreat-Based Program for Violence-Exposed Women Veterans

Given their elevated risk for suicide and barriers to engaging in VHA healthcare, violence-exposed women Veterans represent a specialized population for which expansions to current

📍 VA Connecticut Healthcare System West Haven Campus, West Haven, CT — West Haven, Connecticut

💵 Participants will receive the GRIT in cohorts of approximately 12.

Multimodal Magnetoencephalography and Electroencephalography Exploration of the Acute Effects of THC Exposure on Neural Noise and Information Transmission Within Working Memory Networks

The purpose of this study is to use non-invasive brain imaging methods (MEG and EEG) to characterize the effects of THC on brain activity during learning.

📍 VA Connecticut Healthcare System, Yale School of Medicine — West Haven, Connecticut

Genetic Basis of the Risk and Consequences of Cannabis Exposure in Humans

Cannabis is widely used worldwide and is associated with negative outcomes including cannabis use disorder (CanUD), psychosis, and cognitive impairment amongst others. Given the le

📍 West Haven Veterans Affairs Medical Center — West Haven, Connecticut

Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study II

The purpose of the study is to characterize the acute effects of cannabinoids in women relative to men and to begin probing the mechanisms that may underlie gender differences.

📍 Biological Studies Unit at the VA Connecticut Healthcare System, Yale School of Medicine — West Haven, Connecticut

Study of the Safety, Tolerability, Electrophysiological Effects and Efficacy of DMT in Humans

The goal of this phase 1 study is to investigate the safety and efficacy of dimethyltryptamine (DMT) in individuals with depression and healthy controls. We hypothesize that admini

📍 Biological Studies Unit at the VA Connecticut Healthcare System, Yale School of Medicine, — West Haven, Connecticut

Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans

The purpose of the study is to characterize the acute effects of cannabinoids in women relative to men and to begin probing the mechanisms that may underlie gender differences.

📍 Biological Studies Unit at the VA Connecticut Healthcare System, Yale School of Medicine — West Haven, Connecticut

Acute Effects of THC in Older Adult

The primary objective of this study is to determine if increasing age confers greater vulnerability to the acute A) cognitive (e.g., memory, attention, psychomotor function), B) su

📍 VA Connecticut Healthcare System — West Haven, Connecticut

Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient Study

The overall objective of the proposed study is to determine if Dexmedetomidine HCl (BXCL501) is safe for treatment of alcohol use disorder (AUD) with comorbid posttraumatic stress

📍 VA Connecticut Healthcare System — West Haven, Connecticut

💵 Participants will receive BXCL501 for 28 days.

Effects of Dronabinol in Opioid Maintained Patients

Twenty male and female (ages 18-70) participants with OUD currently receiving methadone or buprenorphine will be enrolled. Prior to their daily methadone or buprenorphine dose and

📍 VA Connecticut Healthcare System — West Haven, Connecticut

💵 Prior to their daily methadone or buprenorphine dose and thus at trough plasma levels of opioid, participants will recei

PK/PD of Oral and Vaporized Delta-9-Tetrahydrocannabinol (THC) in Older Adults

The overarching goal of this double-blind, placebo-controlled, crossover study is to characterize the pharmacokinetic (PK) and pharmacodynamic (PD) effects of the main analgesic an

📍 VA Connecticut Healthcare System — West Haven, Connecticut

💵 Across three, 8-hour test sessions, participants will receive a random sequence of 3 conditions: 5 mg oral THC; 10 mg or

Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study I

The purpose of the study is to characterize the acute effects of cannabinoids in women relative to men and to begin probing the mechanisms that may underlie gender differences.

📍 Biological Studies Unit at the VA Connecticut Healthcare System, Yale School of Medicine — West Haven, Connecticut

Cannabidiol in Opioid Use Disorder and Chronic Pain

This is a randomized, placebo-controlled, crossover human laboratory study investigating the dose-dependent safety and acute effects of Cannabidiol (CBD) on measures of pain and op

📍 Department of Veterans Affairs Hospital — West Haven, Connecticut

💵 Across four test sessions, prior to their daily methadone or buprenorphine dose, and thus at trough plasma levels of opi

Mechanistic Studies of Psilocybin in Headache Disorders

In previous clinical trial work, the investigators observed lasting reductions in headache burden after limited dosing of psilocybin. This purpose of this study is to examine poten

📍 VA Connecticut Healthcare System — West Haven, Connecticut