29 Paid Clinical Research Studies in Chicago, Illinois

Testing a Real-time Electronic Antiretroviral Adherence Monitoring Intervention

The investigators propose using an electronic adherence device that is basically a pill container that can alert when it is not opened at a scheduled time. The investigators will u

📍 University of Illinois Chicago — Chicago, Illinois

Vaccine Hesitancy in Black/African Americans With Rheumatic Diseases

To establish the efficacy of a community-based POL (Popular Opinion Leader) intervention with two different trainings designed to increase COVID-19 vaccine and booster uptake and r

📍 Northwestern University — Chicago, Illinois

Basic Experimental Study of Hippocampal Memory Functions

This project tests the role of the human hippocampus in providing online representation of episodic content and providing the top-down signals to brain networks for visuospatial at

📍 Northwestern Memorial Hospital — Chicago, Illinois

Platelet-rich Plasma for Eyebrows

The purpose of this study is to evaluate the effect of autologous platelet-rich plasma (PRP) in the treatment of mild to moderate eyebrow hypotrichosis. This is a randomized clini

📍 Northwestern University — Chicago, Illinois

Progressive Abduction Loading Therapy

This study attempts to minimize the development of a common movement impairment following stroke known as "flexion synergy" that makes it extremely difficult to reach outward with

📍 Department of Physical Therapy and Human Movement Sciences — Chicago, Illinois

💵 Participants will receive experimental or comparison group therapy as adjuvant to regular in-patient and day-rehabilitat

The Synergistic Effects of AIH and FES in Persons With MS

The purpose of this study is to examine how neuromuscular electrical stimulation (NMES), may synergistically enhance corticospinal excitability in people with relapsing form multip

📍 Shirley Ryan AbilityLab — Chicago, Illinois

Time-restricted Eating Versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers

Approximately 42% of American adults are obese, and this condition is strongly related to the development of colorectal cancer. Innovative lifestyle strategies to treat obesity and

📍 University of Illinois at Chicago — Chicago, Illinois

Pembrolizumab With Chemotherapy for Poorly Chemo-responsive Thyroid and Salivary Gland Tumors

Phase II, 2-cohort, single arm trial treated with the combination of the following two agents: 1. Pembrolizumab (MK3475) 200mg, every three weeks, iv 2. Docetaxel 75mg/m2, every t

📍 University of Chicago Comprehensive Cancer Center — Chicago, Illinois

💵 For accessible tumors only, at week three patients will receive an on-treatment biopsy.

A Pilot Study Testing Onabotulinum Toxin A Versus Incobotulinum Toxin A Injections for Facial Wrinkles

The purpose of this study is to compare the effectiveness of Botox® (Onabotulinum Toxin A) versus Xeomin® (incobotulinum toxin A) for the treatment of forehead and glabellar (verti

📍 Northwestern University Department of Dermatology — Chicago, Illinois

Centering Those Engaged in Transactional Sex: A PrEP Innovation for Getting To Zero

Using a participatory implementation science framework, I will test whether an adapted and community empowered group healthcare model, Centering PrEP+, is a feasible and acceptable

📍 University of Illinois at Chicago — Chicago, Illinois

Transcutaneous Spinal Cord Stimulation in Healthy Adults

The goal of this study is to understand how transcutaneous spinal cord stimulation (tSCS) waveform, modulation frequency, and stimulation location impact lower extremity muscle act

📍 Shirley Ryan AbilityLab — Chicago, Illinois

A Study of Gene Therapy for Classic Congenital Adrenal Hyperplasia (CAH)

This study is designed to evaluate the safety, tolerability, and efficacy of AAV5 based BBP-631 in adult participants diagnosed with classic congenital adrenal hyperplasia.

📍 Ann and Robert H. Lurie Children's Hospital of Chicago — Chicago, Illinois

💵 Participants will receive a single dose of AAV5 based intravenous (IV) BBP-631 and will be followed for safety and effic

Defining the Skin and Blood Biomarkers of Pediatric Atopic Dermatitis

Atopic dermatitis (AD), also known as eczema, is the most common inflammatory skin disorder of children, affecting 10-20% of children and 1-2% of adults. This skin disorder can be

📍 Ann & Robert H. Lurie Children's Hospital of Chicago — Chicago, Illinois

Black Girls Move Physical Activity and Improving Dietary Intake Among Black Adolescent Daughters

Black Girls Move is a school-linked daughter/mother physical activity and dietary behavior program, with 9th and 10th grade students. This program is designed to prevent obesity in

📍 Rush University Medical Center — Chicago, Illinois

Artificial Intelligence (AI)-Based Intraoperative Visualization is Increasingly Integrated Into Robotic Surgery Platforms; However, Its Impact on Surgeons' Cognitive Workload Remains Unclear. This Study Evaluated Perceived Workload Among Console Surgeons and Bedside Assistants According to Different

Robotic surgery is now widely adopted in urology, and the da Vinci Single-Port (SP) platform enables complex procedures through a single multichannel incision, with favorable perio

📍 UI Health — Chicago, Illinois

Skin Elasticity Measurements of the Face and Surgical Scars Stratified by Age and Skin Type

The primary objective of Part A is to compare the change in elasticity measurements at baseline and at 3 months between subjects who have had a resurfacing or tightening procedure

📍 Northwestern University Feinberg School of Medicine, Department of Dermatology — Chicago, Illinois

School-based Support for Pre-school Aged Children With Developmental Disabilities and Delays

This proposal aims to test whether a proposed community-clinical linkage (CCL), an educational-medical linkage model, improves access to school-based services and subsequent child,

📍 UI Health — Chicago, Illinois

Behavioral Chronotype: Impact on Sleep and Metabolism

The purpose of this study is to examine how the timing of eating changes how the body makes and uses energy (metabolism). This study will also examine if metabolism changes with ag

📍 University of Chicago — Chicago, Illinois

Improving Maternal and Child Health Through Prenatal Fatty Acid Supplementation

The purpose of the study is to test whether nutritional supplementation during pregnancy is associated with 1) improved maternal health during pregnancy; 2) improved infant birth a

📍 University of Chicago Medicine — Chicago, Illinois

A Pilot Study Testing Salicylic Acid Peels Versus Glycolic Acid Peels for the Treatment of Melasma

The purpose of this study is to find out the safety and effectiveness of Glycolic Acid Chemical Peels compared to Salicylic Acid Chemical Peels for the treatment of melasma.

📍 Northwestern University Department of Dermatology — Chicago, Illinois

Wearable Airbag Technology to Mitigate Falls in Individuals With High Fall Risk

The purpose of this study is to evaluate the feasibility and efficacy of a smart airbag system that detects and mitigates fall-related impact in individuals with high fall risk.

📍 Shirley Ryan AbilityLab — Chicago, Illinois

Assessment of Paclitaxel-Induced Neuropathy

The purpose of this study is to collect clinical data, blood samples, and self reported symptoms from patients that experience unusually severe neuropathy after treatment with pacl

📍 University of Chicago Comprehensive Cancer Center — Chicago, Illinois

Evaluating a New Sensor That Measures the Health of the Retina in Normally-sighted Subjects

The primary purpose of this study is to evaluate the ability of a new contact lens electrode to record a measurable electroretinogram (ERG). ERG sensors in various forms have been

📍 UIC Department of Ophthalmology & Visual Sciences — Chicago, Illinois

Phase 2 Trial of Neoadjuvant Weekly Carboplatin Plus Paclitaxel in Triple Negative Breast Cancer

Nonrandomized, open label, single arm, Simon's two stage MinMax design trial of neoadjuvant weekly carboplatin plus paclitaxel, followed by doxorubicin and cyclophosphamide in pati

📍 University of Illinois — Chicago, Illinois

💵 Subjects will receive carboplatin (Area Under the Curve (AUC) 2 mg/mL/min) + paclitaxel (80 mg/m2) Carboplantin plus Pac

Pembrolizumab and Lenvatinib in Clear Cell Ovarian Cancer

This research study is being done to test the efficacy and safety of combining the study drugs pembrolizumab and lenvatinib in patients with clear cell ovarian cancer. The names o

📍 University of Chicago Medicine — Chicago, Illinois

💵 Participants will receive study treatment until progression of disease or unacceptable toxicity.

Church-based Intervention to Improve Physical Function

This is a 12-month multi-level behavioral cluster randomized trial testing a church-based intervention to improve physical function (PF) in Americans with PF limitations.

📍 Rush University Medical Center — Chicago, Illinois

Mobile Health Interventions to Prevent Heart Disease After Hypertensive Disorders of Pregnancy

The purpose of this research is to study digital health interventions to prevent cardiovascular disease in individuals who have had a hypertensive disorder of pregnancy (HDP).

📍 Northwestern University, Dept. of Cardiology — Chicago, Illinois

💵 If randomized to the control arm, the participant will receive care as usual.

Wearable Gait Sensors

This research study is testing body-worn sensors to measure movement during simple tests of coordination, in order to evaluate the progression and severity of Spinocerebellar ataxi

📍 University of Chicago — Chicago, Illinois

Physical Activity Targeting Metabolic Syndrome for Prevention of Breast Cancer in SAI Women

This study aims to to improve physical activity and metabolic outcomes for breast cancer prevention in South Asian Indian immigrant women.

📍 Rush University College of Nursing — Chicago, Illinois