32 Paid Clinical Research Studies in Baltimore, Maryland

The HOPE Study: Characterizing Patients With Hepatitis B and C

This is an observational, longitudinal, prospective study for sample collection and evaluation for future therapy or disease progression of chronic hepatitis B and C. Participants

📍 Institute of Human Virology, University of Maryland School of Medicine — Baltimore, Maryland

💵 In this sub-study, participants will receive an approved nucleos(t)ide analogue prospectively observed on therapy for ch

Antibiotic Treatment and Long-term Outcomes of Patients With Pseudomyxoma Peritonei of Appendiceal Origin

The purpose of this study is to determine the impact of antibiotic therapy on the disease progression and overall survival of patients with Pseudomyxoma Peritonei (PMP).

📍 Mercy Medical Center — Baltimore, Maryland

C-Raven, a Virtual Tobacco Cessation Intervention in Residency Clinics

In a residency clinic in Baltimore, the investigators propose to conduct a pilot RCT comparing a) an avatar-delivered computerized intervention (CI) for tobacco cessation augmented

📍 Johns Hopkins University School of Medicine — Baltimore, Maryland

💵 Intervention: Computer-Delivered Intervention (CDI) Session 1: Following the baseline assessment, participants will rec

Neoadjuvant Enoblituzumab (MGA271) in Men With Localized Intermediate and High-Risk Prostate Cancer

This study evaluates the safety, anti-tumor effect, and immunogenicity of Enoblituzumab given before radical prostatectomy. All patients will receive Enoblituzumab for 6 weekly dos

📍 Johns Hopkins Sidney Kimmel Comprehensive Cancer Center — Baltimore, Maryland

💵 All patients will receive Enoblituzumab for 6 weekly doses beginning 50 days prior to radical prostatectomy.

Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus

The purpose of this study is to determine if there are any early changes in DNA markers of blood and esophageal tissue in people with gastric reflux, Barrett's esophagus or esophag

📍 Johns Hopkins Hospital — Baltimore, Maryland

Preventing Postpartum Depression in Immigrant Latinas

Postpartum depression (PPD) affects 10-20% of women, with immigrant Latinas disproportionately affected. PPD prevention and treatment is limited among immigrant Latinas due to an a

📍 Johns Hopkins University School of Medicine — Baltimore, Maryland

A Phase 1/2a to Evaluate the Safety and Efficacy of Adipose Tissue Allograft (BRC-OA) in Patients With Osteoarthritis of the Knee

The purpose of this study is to evaluate the safety profile of BRC-OA for pain treatment in patients with mild to severe OA of the knee, focusing particularly on two distinct doses

📍 LifeBridge Health — Baltimore, Maryland

💵 The initial 3 subjects will receive a 2 mL dose of BRCOA, and if deemed safe and well-tolerated by the investigator, the

Innovative Approaches to Gauge Progression of Sturge-Weber Syndrome

This study has three aims that hope to expand the knowledge on the cause of Sturge-Weber Syndrome (SWS) and improve clinical care of Sturge-Weber Syndrome patients.

📍 Kennedy Krieger Institute — Baltimore, Maryland

Clinic-based HIV Identification and Prevention Project Using Electronic Resources

Hybrid Type II effectiveness-implementation trial to investigate whether electronic medical and sexual history data collection with HIV risk categorization/scoring will increase pr

📍 Johns Hopkins Health System — Baltimore, Maryland

Addressing Post-Intensive Care Syndrome Among Survivors of COVID (APICS-COVID)

This study will assess the relationship between early unmet needs after hospital discharge and subsequent clinical outcomes among survivors of acute respiratory failure. The invest

📍 Johns Hopkins Hospital — Baltimore, Maryland

💵 While in the ICU, participants will receive usual clinical care in this observational study.

Safety and Efficacy of the Bacteriophage Preparation, ShigActive™, in a Human Experimental Model of Shigellosis

The study is a first-in-human Phase 1/2a randomized, double-blind, placebo-controlled trial to assess the clinical safety and efficacy of ShigActive in healthy adults with experime

📍 University of Maryland, Baltimore, University of Maryland School of Medicine, Center for Vaccine Development and Global Health — Baltimore, Maryland

Effect of Topical Sulforaphane on Skin Aging and With Ultraviolet and Visible Light Exposure

The study is to compare the expression of both keratin 16 and 17 before and after application of sulforaphane on both photoprotected and photoexposed area, and to determine whether

📍 Cutaneous Translational Research Program, Department of Dermatology, Johns Hopkins University School of Medicine — Baltimore, Maryland

CVD 37000: Immunity and Microbiome Studies at Intestinal and Systemic Sites in Ty21a Vaccinated Adults

This is an open-label, non-randomized study. The purpose of this study is to better understand how vaccines against typhoid fever affect the normal immune system and bacteria in th

📍 Universtiy of Maryland, Baltimore, Center for Vaccine Development and Global Health — Baltimore, Maryland

Pathways to Improved Adolescent Mental Health in Conflict Affected Families

The study combined a youth-friendly economic empowerment program (Rabbits for Resilience (RFR) with a gender equality couple curriculum program (HIKA) to advance knowledge on the c

📍 Johns Hopkins University School of Nursing — Baltimore, Maryland

Digital Literacy Intervention to Address Support, Literacy and Communication in Older Adults

The investigators propose a person-directed, values-based digital literacy intervention to address the community-identified barriers of health literacy, health communication and so

📍 Johns Hopkins School of Nursing — Baltimore, Maryland

💵 Each participant will receive 4-6 home visits with 3-4 interim phone calls based on the participant's individual digital

Analysis of the Microbiome in Rosacea

The skin and gut microbiome of rosacea patients differs from individuals without rosacea and that the microbiome suffers from unique derangements in rosacea patients following anti

📍 Cutaneous Translational Research Program, Department of Dermatology — Baltimore, Maryland

Reduced Opioid Prescription After Laparoscopic Hysterectomy

Given the nationwide epidemic of opioid use and abuse (in part due to over prescription), this study aims at addressing the need for opioid prescription after laparoscopic hysterec

📍 Johns Hopkins Hospital — Baltimore, Maryland

Intravesical Gemcitabine and Docetaxel for BCG naïve Non-muscle Invasive Bladder Cancer

A single-arm, two-stage, open-label, phase 2 study investigating the safety and efficacy of intravesical gemcitabine/docetaxel for bacillus Calmette-Guerin (BCG)-naïve patients wit

📍 Johns Hopkins University: Sidney Kimmel Comprehensive Cancer Center — Baltimore, Maryland

💵 All participants will receive an induction course of gemcitabine/docetaxel instillations (administered once a week for s

Pain Self-Management and Treatment Engagement for Patients Taking Opioids

The goal of this study is to learn if Pain Self-Management (PSM) can improve chronic pain care in individuals with opioid misuse or opioid use disorder (OUD) The main questions it

📍 Comprehensive Care Practice — Baltimore, Maryland

💵 Participants will: * Take part in the PSM program or receive standard care for 12 weeks after enrolling in the study *

Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy

This research is being done to evaluate the short term and long term effects of ketogenic diets on measures of cardiovascular health. Such measures include cholesterol levels, bloo

📍 Johns Hopkins University — Baltimore, Maryland

💵 If participants agree to be in this study, the investigators will ask the participants to do the following things: At I

Psilocybin Treatment of Major Depressive Disorder With Co-occurring Alcohol Use Disorder

The purpose of this study is to determine whether psilocybin, a hallucinogenic drug, is effective in reducing depressive symptoms and amount of drinking in patients with co-occurri

📍 Johns Hopkins Center for Psychedelic and Consciousness Research — Baltimore, Maryland

💵 After primary endpoints are measured, all volunteers will receive a second, unblinded intervention with a single high do

Vital Pulp Treatment in Primary Teeth

In primary teeth, decay that is near the pulp (tooth nerve)is treated with either a pulpotomy or indirect pulp treatment if the tooth is not going to be extracted A pulpotomy invol

📍 University of Maryland School of Dentistry — Baltimore, Maryland

Behavioral Pharmacological Examination of a Novel Buprenorphine Induction Method Among Individuals Who Use Fentanyl

The opioid overdose epidemic has persisted for several decades and is now further complicated by the permeation of fentanyl into the illicit opioid supply. While the effectiveness

📍 Johns Hopkins School of Medicine — Baltimore, Maryland

💵 In a single-ascending dose design, the investigators will incrementally assess the tolerability of 4, 8, 16, and 24 mg o

Developing a Learning COmmunity to Increase eNgagemeNt and Enrollment in Cardiovascular Clinical Trials (CONNECT)

The CONNECT: "Developing a learning COmmunity to increase eNgagemeNt and Enrollment in cardiovascular Clinical Trials" is comprehensive, participant-centered learning platform desi

📍 Johns Hopkins University School of Nursing — Baltimore, Maryland

DMID 23-0015; Lassa Fever CVD 1000

This study proposes the evaluation of a novel, first-in-human Lassa fever vaccine based on the complete Lassa glycoprotein complex (GPC) antigen. The antigen will be presented on a

📍 University of Maryland, Baltimore, University of Maryland School of Medicine, Center for Vaccine Development and Global Health — Baltimore, Maryland

Behavioral Weight Loss for Cancer Survivors in Maryland: A Trial With Adaptive Interventions

The objective of the HELPLINE Weight Loss Program is to determine the comparative effectiveness of two active multi-component, augmented interventions for cancer survivors with ove

📍 Johns Hopkins ProHealth — Baltimore, Maryland

💵 Intensive Helpline in early non-responders (additional 6 months) All participants will receive * written Johns Hopkins

The Very Large Database of Lipids

Closer examination of granular lipid data in a large population offers numerous opportunities to generate new knowledge, ranging from studies examining concordance between commonly

📍 Johns Hopkins University — Baltimore, Maryland

A Study to Learn How Fluconazole, Carbamazepine and Itraconazole Affect How the Body Processes ASP3082 in Healthy Adults

Genes give your body instructions on how to make proteins. Proteins are needed to keep the body working properly. Many types of cancer are caused by changes in certain genes, makin

📍 Parexel — Baltimore, Maryland

The Sedentary to Active Rising to Thrive (START) Trial

The goal of this behavioral clinical trial is to compare two different ways of becoming less sedentary and more active in 60 older adults at elevated risk of becoming frail. The m

📍 Johns Hopkins ProHealth — Baltimore, Maryland

GLP-1 and Hypoglycemia

Low blood sugar can negatively affect how blood vessels function, and this can lead to an increase in the risk for heart attacks, strokes and other problems related to the stiffeni

📍 University of Maryland, Baltimore — Baltimore, Maryland

Feasibility and Safety Study of Parent-to-Child Nasal Microbiota Transplant

This feasibility and safety pilot study looks to determine whether transferring a parents healthy, diverse nasal microbiota to the participant's infant(s) will create a healthy, di

📍 Johns Hopkins University — Baltimore, Maryland

Pain Self-Management and Patient-Oriented Dosing for Pain and in Retention Opioid Treatment

This study seeks to improve the treatment of chronic pain in people who are taking buprenorphine (also known as Suboxone, Subutex, Zubsolv). The research study is testing two diff

📍 Alcohol and Drug Abuse Program (ADAP) - UM Addiction Treatment Center — Baltimore, Maryland

💵 Participants will receive $50 compensation for each survey visit completed (up to $250 over one year) and can receive up