13 Paid Clinical Research Studies in Belmont, Massachusetts

Electronic Cigarettes and Reactivity to Smoking Cues

The purpose of this study is to determine whether electronic cigarettes can reduce reactivity to smoking-related cues.

📍 Mclean Hospital Imaging Center — Belmont, Massachusetts

💵 The only source of nicotine participants will receive during the study will come from NRT.

Development of LabPatch-alcohol as a Noninvasive Skin Patch to Detect Blood Alcohol Concentrations

This study is designed to test LabPatch-alcohol, a wearable, non-invasive biosensor Band-Aid like patch that is designed to detect real-time changes in interstitial alcohol concent

📍 McLean Hospital — Belmont, Massachusetts

Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Study 1.2 (Stress Manipulation)

This study investigates how remitted individuals with past major depressive disorder (MDD) make approach-avoidance decisions and which brain regions are implicated in such decision

📍 McLean Hospital — Belmont, Massachusetts

Synaptic Mechanisms of Intermittent Theta Burst Stimulation for Major Depressive Disorder

Many people with depression do not get better with standard treatments like medications or talk therapy. Transcranial magnetic stimulation (TMS) is a non-invasive brain stimulation

📍 McLean Hospital — Belmont, Massachusetts

Beyond Monoamines: The Role of the Nociceptin/Orphanin FQ Receptor in Major Depression

This study looks at the role of the Nociceptin/Orphanin FQ receptor system in the brain of individuals with current or past major depressive disorder (MDD). It also examines how in

📍 McLean Hospital — Belmont, Massachusetts

Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Pharmacological Manipulation

The study will investigate whether a nociceptin receptor antagonist will normalize neural and behavioral processes of approach/avoidance decision-making in unmedicated individuals

📍 Mclean Hospital — Belmont, Massachusetts

Stress Dynamics and Familial Risk for Depression in Female Adolescents

Stress and a parental history of major depressive disorder (MDD) are among the strongest risk factors for future development of MDD. Studies have shown that having a parental histo

📍 McLean Hospital — Belmont, Massachusetts

Neural Correlates of Stress and Perceived Control in Adolescent Depression

Lack of perceived control, particularly during stress, has been critically implicated in major depressive disorder (MDD) and anhedonic symptoms, especially among female adolescents

📍 McLean Hospital — Belmont, Massachusetts

Mechanisms and Predictors of Change in App-Based Mindfulness Training for Adolescents

A growing body of research implicates rumination as being a transdiagnostic risk factor involved in the development of depression and anxiety in youth. Critically, mindfulness medi

📍 McLean Hospital — Belmont, Massachusetts

Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans

This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study satiety in healthy individuals. TMS is a noninvasive way of stimulating the brain,

📍 McLean Hospital — Belmont, Massachusetts

Early Life Stress and Depression: Molecular and Functional Imaging

Severe childhood adversity accounts for a large portion of psychiatric illness, and an increased risk for major depressive disorder (MDD). For some individuals, childhood adversity

📍 McLean Hospital — Belmont, Massachusetts

Use of Ketosis in Modulating Metabolic Pathways in Bipolar Disorder

The goal of this clinical trial is to test how specific components of diet affect brain function and behavior for individuals with bipolar. The main question it aims to answer is h

📍 McLean Hospital — Belmont, Massachusetts

Pharmacologic Augmentation of TMS for Depression With D-serine

The goal of this study is to test whether combining D-serine with 30 treatments of a) iTBS and b) 18-Hz protocols will enhance clinical outcomes compared to rTMS with placebo (i.e.

📍 McLean Hospital — Belmont, Massachusetts

💵 Therefore, all patients will receive standard of care treatment combined along with either placebo or d-serine, designed