17 Paid Clinical Research Studies in Charlestown, Massachusetts

The Wandering Nerve: Gateway to Boost Alzheimer's Disease Related Cognitive Performance

In this research study the investigators want to find out if a non-invasive electrical brain stimulation method called RAVANS (also called tVNS) can have a beneficial effect on cog

📍 Massachusetts General Hospital — Charlestown, Massachusetts

TMS With Real-time E-field and EEG Source Imaging

The goal of this study is to develop and validate an approach for accurate targeting and stimulation of brain networks using transcranial magnetic stimulation (TMS) using informati

📍 MGH at the Navy Yard — Charlestown, Massachusetts

Reconnecting to Ourselves and Others in Virtual Meetings (ROOM)

This study aimed to determine the feasibility and acceptability of delivering Resilience Training in multi-user virtual reality.

📍 Massachusetts General Hospital — Charlestown, Massachusetts

Conditioning & Open-Label Placebo (COLP) for Opioid Management in Intensive Inpatient Rehabilitation

The use of the conditioning open-label placebo (COLP) paradigm will be studied as a dose extension method to lower opioid dosage in patients with spinal cord injury, polytrauma, an

📍 Spaulding Rehabilitation Hospital — Charlestown, Massachusetts

💵 Afterward, subjects will receive a 50% dose + COLP for three days.

Individual Closed-Loop Neuromodulation Therapy for Alzheimer's Disease

The project is a placebo-controlled study that aims to use closed-loop transcranial alternating current stimulation (tACS) to study patients with symptoms of mild cognitive impairm

📍 Massachusetts General Hospital — Charlestown, Massachusetts

Neurobehavioral Mechanisms of Social Isolation and Loneliness in Serious Mental Illness

The proposed research will test the hypothesis that objective social isolation and loneliness are linked to neurobehavioral mechanisms involved in social perception and motivation

📍 Massachusetts General Hospital — Charlestown, Massachusetts

Diffusion MRI in Heart Failure

The development of symptomatic heart failure is frequently preceded by a pre-clinical period of structural remodeling in the heart. The remodeling process driving this transition,

📍 Massachusetts General Hospital — Charlestown, Massachusetts

MDMA-assisted Therapy for Fibromyalgia

Fibromyalgia is a debilitating chronic pain disorder. Based on prior research with MDMA, it can be hypothesized MDMA-assisted therapy in fibromyalgia patients may increase the rang

📍 Massachusetts General Hospital — Charlestown, Massachusetts

💵 Participants will receive an initial dose of 100 mg of MDMA.

Modulation of Brain Oscillations Underlying Working Memory

This study will use novel transcranial alternating current stimulation (tACS) protocols and electroencephalography (EEG) to modulate and measure brain oscillations that underlie wo

📍 Martinos Center for Biomedical Imaging — Charlestown, Massachusetts

The Effects of Auditory Stimulation During Sleep on Brain Networks in Schizophrenia

In this research study the investigators will use sleep headbands to measure brain rhythms and to improve their coordination across brain regions. The headbands will be worn at hom

📍 Massachusetts General Hospital — Charlestown, Massachusetts

VGAIT for Chemotherapy-induced Peripheral Neuropathy

Perform a feasibility study on imagined acupuncture treatment of Chemotherapy-induced peripheral neuropathy (CIPN)

📍 Massachusetts General Hospital — Charlestown, Massachusetts

💵 Participants will receive 16 sessions of VGAIT over 8 weeks remotely through the zoom.

Effects of Caffeine on Reinforcement Learning in Healthy Adults Using PET/MRI

This research study aims to determine whether and how caffeine intake affects learning process through reward feedback compared to placebo. The data acquired from this study would

📍 Athinoula A. Martinos Center for Biomedical Imaging — Charlestown, Massachusetts

OBSERVE: Biomarkers in Individuals at Risk for Prion Disease

We are doing this research to identify biomarkers in individuals who are at-risk for familial prion disease. We hope to use these biomarkers to predict timing of disease onset in p

📍 Alzheimer's Clinical and Translational Research Unit — Charlestown, Massachusetts

💵 Travel support and stipend is provided for interested individuals.

Linked Outcomes in Various EEG-Hyperscanning Setups

The goal of this observational study is to investigate how brains of healthy controls respond when they interact with their romantic partner compared to when they interact with a s

📍 Spaulding Rehabilitation Hospital — Charlestown, Massachusetts

💵 The ILS task includes three conditions, one where both participants receive light stimulation simultaneously, another tw

PET Imaging Evaluation of [11C]SY08

The overall goal of the proposed research is to evaluate the use of \[11C\]SY08 as a PET radiotracer for aggregated alpha synuclein (αS) in individuals with Parkinson's disease (PD

📍 MGH — Charlestown, Massachusetts

Value of PET/MR Enterography in the Assessment of Crohn's Disease Using a Collagen-binding Radiotracer.

In this study twenty-five (25) subjects with Crohn's disease scheduled for possible surgical intervention will be recruited for this study and a PET/MR scan using the collagen-bind

📍 Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School — Charlestown, Massachusetts

💵 Study subjects will receive an injection of \[68Ga\]CBP8 followed by whole body MR-PET imaging acquired at 1 hour.

PET/MRI/EEG Imaging Study in Epilepsy

This study aims to better understand how epilepsy alters brain function through neuroimaging of healthy people and people with epilepsy. The study investigates how changes in brain

📍 Athinoula A. Martinos Center — Charlestown, Massachusetts