23 Paid Clinical Research Studies in Detroit, Michigan

Opioid-Free Pain Protocol After Shoulder Arthroplasty

This randomized, single blinded, clinical trial aims to investigate the efficacy of a multimodal pain control regimen for shoulder arthroplasty. Patients who receive a multimodal p

📍 Henry Ford Health — Detroit, Michigan

Randomized Controlled Trial Examining the Efficacy of Botulinum Toxin in Biopsy Scar Minimization

The proposed study seeks to evaluate the scar reduction capacity of BTA on excision/biopsy wounds compared to the control (normal saline) in a double-blinded randomized control tri

📍 Henry Ford Health System — Detroit, Michigan

Optimizing Phototesting and Investigating Photobiology of Visible Light

Specific Aim 1: To determine the impact of spectral composition of the VL+UVA1 source on the associated biologic effects. Specific Aim 2: To investigate differential responses of

📍 Henry Ford Medical Center — Detroit, Michigan

Coping With Glioblastoma: A Study of Communication Between Physicians, Patients, and Caregivers

The purpose of this study is to learn more about the way physicians communicate with brain tumor patients. This study will look at how oncologists provide information about brain t

📍 Henry Ford Hospital — Detroit, Michigan

Efficacy Evaluation of Products Against Long Wavelength Ultraviolet A1 and Visible Light Induced Biological Effects

The purpose of this study is to evaluate the efficacy of topical products in providing protection against the visible light and ultraviolet A1 (UVA1) part of sunlight. Ultraviolet

📍 Department of Dermatology, Henry Ford Medical Center, 3031 West Grand Boulevard, — Detroit, Michigan

Depth of Botulinum Neurotoxin Injection for Treatment of Glabellar Lines

STUDY QUESTION: Does the depth of injection of onabotulinumtoxinA neurotoxin in the glabellar complex affect efficacy of the BoTN for the improvement of glabellar frown lines? STUD

📍 Henry Ford Health System — Detroit, Michigan

A(B)VD Followed by Nivolumab as Frontline Therapy for Higher Risk Patients With Classical Hodgkin Lymphoma (HL)

The aim of this study is to improve the chance of cure for people with higher risk Hodgkin lymphoma. The purpose of the Phase I study is to test any good and bad effects of the stu

📍 Karmanos Cancer Institute — Detroit, Michigan

💵 Patients may receive steroid therapy if steroids are tapered down to 10mg or less by 4 weeks after initiating A(B)VD to

Longitudinal Neuroimaging in Sturge-Weber Syndrome

In this project the accuracy of a novel, rapid magnetic resonance imaging (MRI) approach to detect brain abnormalities in patients with Sturge-Weber syndrome (SWS) will be tested;

📍 Wayne State University / Children's Hospital of Michigan — Detroit, Michigan

Isatuximab During Stem Cell Collection and Transplant in Patients With Multiple Myeloma and Lymphoma

The purpose of this study is to see if Isatuximab can alter the immune system in patients with multiple myeloma or lymphoma upon recovery from the autologous stem cell transplantat

📍 Karmanos Cancer Institute — Detroit, Michigan

💵 On one arm (control arm), participants will receive standard transplant procedures and on the other arm (experimental ar

Central Apnea in Heart Failure: Physiological Mechanisms to Inform Treatment

Central sleep apnea (CSA) is common in patients with heart failure and those using opioid analgesics. Unfortunately, effective treatment of central apnea remains elusive, pressure

📍 John D. Dingell VA Medical Center, Detroit, MI — Detroit, Michigan

Maneuvers to Reduce Laparoscopic Pain

Laparoscopic surgery has revolutionized surgical care by reducing morbidity and improving post operative recovery. Laparoscopic surgery involves the use of carbon dioxide for insuf

📍 Henry Ford Hospital — Detroit, Michigan

Understanding Non-invasive Vagus Nerve Stimulation Effects in PTSD

The goal of this study is to determine how non-invasive brain stimulation (delivered through the ear called vagus nerve stimulation) affects fear learning processes in people who h

📍 Tolan Park Research Clinic, Wayne State University — Detroit, Michigan

💵 Participants will be compensated for their time.

Perioperative Cemiplimab for Resectable Non-Small Cell Lung Cancer With High PD-L1

This is a single arm phase II trial enrolling patients with stage II-IIIA non-small cell lung cancer whose disease is deemed amenable for surgical resection and has a PD-L1 level o

📍 Henry Ford Health — Detroit, Michigan

💵 Patients will receive cemiplimab for 3 cycles followed by surgical resection.

Fractionated 1927-nm Non Ablative Thulium Laser in Treating Post Inflammatory Hyperpigmentation

To study the effect of fractionated 1927-nm non ablative thulium laser in reduction of post inflammatory hyperpigmentation (PIH) using a validated and reproducible model for studyi

📍 Henry Ford Medical Center — Detroit, Michigan

Sleep Disordered Breathing With Opioid Use

There is an increased risk for sleep disordered breathing (SDB), sleep-related hypoventilation and irregular breathing in individuals on chronic prescription opioid medications. Al

📍 John D. Dingell VA Medical Center, Detroit, MI — Detroit, Michigan

Ondansetron Use for Preventing Pruritus in Patients Undergoing Cesarean Section

Opioids are often added with a local anesthetic to enhance the duration and quality of spinal anesthesia for cesarean delivery patients. However, spinal opioids are associated with

📍 Detroit Medical Center- Hutzel Women's Hospital — Detroit, Michigan

Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment

Central sleep apnea (CSA) is common in patients with heart failure and those using opioid analgesics. Unfortunately, effective treatment of central apnea remains elusive, pressure

📍 John D. Dingell VA Medical Center, Detroit, MI — Detroit, Michigan

Integrating the Youth Nominated Support Team (YST) With CBT for Black Youth With Acute Suicide Risk: Aim 2b

This is a second pilot study being completed based on lessons learned from the Aim 2a feasibility pilot study (NCT06941311). Following modifications, the investigators are testing

📍 Children's Hospital of Michigan (CHM) Emergency Department — Detroit, Michigan

💵 Participants will receive 12-14 sessions of CBT-SP in addition to YST.

Project 4: ACHIEVE PATHFINDER

ACHIEVE-P4: PATHFINDER is a randomized, blinded clinical trial of portable air cleaners (PAC) provided at the time of hospital discharge to Heart Failure (HF) patients. It will be

📍 Henry Ford Health — Detroit, Michigan

💵 Participants will receive two PACs at discharge and an indoor PM2.5 sensor.

Increasing Knowledge and Interest in Cancer Clinical Trials

This trial investigates how well a video-based clinical trial education session works in increasing knowledge and interest in cancer clinical trials among individuals in the metrop

📍 Wayne State University/Karmanos Cancer Institute — Detroit, Michigan

HEART Camp Connect -Promoting Exercise in Adults With Heart Failure With Preserved Ejection Fraction

The goal of this study is to learn more about patients with heart failure with preserved ejection fraction (HFpEF) and exercise. Investigators want to see if meeting with a coach i

📍 Henry Ford Health System — Detroit, Michigan

Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation

The goal of this clinical trial is to evaluate the effects of a home-based exercise program using mobile technology on physical activity and capacity, frailty and muscle mass, and

📍 Henry Ford Health — Detroit, Michigan

💵 Subjects will receive reminders from a smartphone app (Datos) to wear the watch.

Nonopioid Analgesia After Labral Surgery

This is a randomized, single blinded, standard of care controlled clinical trial. This project aims to compare postoperative pain control in patients in two treatment arms of rotat

📍 Henry Ford Health System — Detroit, Michigan