26 Paid Clinical Research Studies in Rochester, Minnesota

Engaging Adolescents in Decisions About Return of Genomic Research Results

Recent recommendations to return children's results for adult-onset conditions to parents anytime whole exome or genome sequencing is performed, as well as growing expectations to

📍 Michelle McGowan — Rochester, Minnesota

AAV8-hCocH for Cocaine Use Disorder

The purpose of this study is to test the safety of a novel gene viral vector treatment for adults with cocaine use disorder-sustained remission. This gene regulates an enzyme (coca

📍 Mayo Clinic in Rochester — Rochester, Minnesota

Optimizing the Patient Experience Through Provider Coaching or Communication Intervention

Hypothesis: Clinicians who receive patient experience coaching or communication classes have improved patient satisfaction scores and improved clinician satisfaction.

📍 Mayo Clinic in Rochester — Rochester, Minnesota

Smartphones Aggravating Anxiety Symptoms

The goal of this study is to assess if excessive use of smartphone apps of social media can impact a person's mental health. The study is aimed at improving the usage of smartphone

📍 Mayo Clinic Minnesota — Rochester, Minnesota

Long-Term Transcutaneous Stimulation and Essential Tremor: A PET Study

Essential tremor (ET) is the most common movement disorder in the United States and affects up to 5% of the population. ET patients experience involuntary shaking of the hands, hea

📍 Mayo Clinic in Rochester — Rochester, Minnesota

💵 Once the maximum tolerable stimulation level has been identified, subjects will receive stimulation at that level during

Autologous Culture Expanded Adipose Derived MSCs for Treatment of Painful Hip OA

Will injection(s) of autologous culture-expanded AMSCs be safe and efficacious for treatment of painful Hip OA, and if so, which dosing regimen is most effective?

📍 Mayo Clinic in Rochester — Rochester, Minnesota

💵 Subjects will receive either a single dose of 30 million autologous culture-expanded adipose-derived mesenchymal stromal

Astronaut Vision Issues in a Ground Analog Population: Polycystic Ovary Syndrome

The investigators have documented a genetic predisposition for some astronauts to develop ophthalmologic issues (e.g., choroidal folds, cotton wool spots, optic disc edema). Women

📍 Mayo Clinic — Rochester, Minnesota

A Study of Oral Kavalactones Effect on Nurses

This research study is being done to assess the impact of taking Kava extract (Piper methysticum), a dietary supplement on cortisol in a healthy nursing population.

📍 Mayo Clinic Minnesota — Rochester, Minnesota

Registry for Mayo Clinic Adult Congenital Heart Disease Control Population

This research study is being done to provide comparative data to the Mayo Clinic Adult Congenital Heart Disease Registry.

📍 Mayo Clinic Minnesota — Rochester, Minnesota

Surface EMG Testing on Swallowing in EoE Patients

Evaluating swallowing food with surface electromyography (EMG) machine in patients with Eosinophilic Esophagitis

📍 Mayo Clinic — Rochester, Minnesota

Evaluating Raised Intracranial Pressure Using MR Elastography

Investigators will compare magnetic resonance (MR) elastography measurements to other forms of noninvasive methods of detecting raised intracranial pressure, including optical cohe

📍 Mayo Clinic in Rochester — Rochester, Minnesota

Exercise-stimulated Muscle Glucose Uptake in Upper Body Obesity

The purpose of this study is to provide the first integrated examination of the interaction between muscle insulin action and exercise-stimulated muscle glucose uptake in obesity f

📍 Mayo Clinic in Rochester — Rochester, Minnesota

Voyage: Real-World Impact of the Multi-target Stool DNA Test on CRC Screening and Mortality

The purpose of this study is to gather information about the long term health of people who have been prescribed the Cologuard test, which is used for colorectal cancer (CRC) scree

📍 Mayo Clinic — Rochester, Minnesota

Natural History of Shoulder Pathology in Manual Wheelchair Users

Over 300,000 people in the United States have spinal cord injuries and many use manual wheelchairs for mobility. Most manual wheelchair users will develop shoulder injuries and pai

📍 Mayo Clinic — Rochester, Minnesota

ADAPT Study: Long-term Safety Study of INZ-701 in Patients With ENPP1 Deficiency and ABCC6 Deficiency

The purpose of this study (Study INZ701-304 \[ADAPT\]) is to assess the long-term safety of INZ-701 in patients with ENPP1 Deficiency or ABCC6 Deficiency who have received INZ-701

📍 Mayo Clinic — Rochester, Minnesota

💵 The study will consist of a 30-day Screening Period, followed by an open-label Treatment Period during which all partici

Intrarenal Microvasculature in ADPKD

The primary objective of this study is to evaluate the use of Super-resolution ultrasound (SRU) to assess the intrarenal microvasculature in patients with Autosomal Dominant Polycy

📍 Mayo Clinic — Rochester, Minnesota

Determination of Baseline Levels for Prostate Cancer-Derived Extracellular Vesicles Following Local Treatment of Prostate Cancer

This study is being done to determine whether levels of prostate cancer derived extracellular vesicles from blood and urine specimens correlate with response to primary local treat

📍 Mayo Clinic in Rochester — Rochester, Minnesota

Improving Implementation of Evidence-based Approaches and Surveillance to Prevent Bacterial Transmission and Infection

Surgical site infections (SSIs) are associated with increased patient morbidity, mortality, and healthcare costs. ESKAPE (Enterococcus, S. aureus, Klebsiella, Acinetobacter, Pseudo

📍 Mayo Clinic — Rochester, Minnesota

Satisfaction and Feasibility Evaluation of an Electronic Massager Compared to Massage Therapist-delivered Massage

The objective of this study is to evaluate the practicality and acceptability of using an electronic massager. Additionally, it aims to compare user satisfaction between the experi

📍 Mayo Clinic — Rochester, Minnesota

💵 The order in which participants will receive each massage will be determined by randomization.

Mixed-Methods Evaluation of Short-, Medium-, and Long-Term Outcomes Following Hip Treatment

This study, titled "Mixed-Methods Evaluation of Short-, Medium-, and Long-Term Outcomes Following Hip Treatment," aims to assess the long-term effectiveness of treatments for pedia

📍 Mayo Clinic in Rochester — Rochester, Minnesota

LLLT to Reduce Low Back Pain

The purpose of this research study is to gather information on the effectiveness of the Trident low-level laser therapy (LLLT) in combination with clinical patient education manual

📍 Mayo Clinic — Rochester, Minnesota

💵 All patients will receive two self-help patient education manuals.

A Study to Evaluate the Safety, Tolerability, and Effects on Blood and Urine Markers of Single Ascending Dose of GSK4771261 in Healthy Participants and Participants With Autosomal Dominant Polycystic Kidney Disease

This is a study where a new drug, called GSK4771261 is being tested. Neither the study doctors, study staff or participants will be aware of what treatment is being given. Part A i

📍 GSK Investigational Site — Rochester, Minnesota

A Study of Pulmonary Hypertension Peripheral Limitations

The investigators are doing this research study to compare whole body aerobic training with isolated leg training (with weights) and its impact on effectiveness in symptoms and qua

📍 Mayo Clinic in Rochester — Rochester, Minnesota

Cohort Study of Pancreatic Cancer Risk

This study is designed to develop a cohort of individuals without pancreatic cancer, but who are at increased risk of developing it due to family history or genetic predisposition.

📍 Mayo Clinic — Rochester, Minnesota

Collecting Blood and Tissue Samples From Family Members of Patients With Pancreatic Diseases, Pancreatic Cancer, and Melanoma

RATIONALE: Collecting and storing samples of blood and tissue from family members of patients with cancer to test in the laboratory may help the study of cancer in the future. PUR

📍 Mayo Clinic Cancer Center — Rochester, Minnesota

A Study of Electrocardiogram and Focused Cardiac Ultrasound for Enhanced Cardiac Disease Screening

The purpose of this study is to evaluate and compare the effectiveness of active screening for SHD in asymptomatic outpatients referred for an ECG, using a combination of AI-ECG an

📍 Mayo Clinic — Rochester, Minnesota