32 Paid Clinical Research Studies in Rochester, New York

DB RCT for Specialized Phototherapy in Parkinson's Disease.

This is a pivotal study to determine whether light therapy can improve non-motor and motor function in Parkinson's disease, on top of current best medical treatment.

📍 University of Rochester — Rochester, New York

A Study of Cognitive Changes in Patients Receiving Brain Radiation

Cranial radiation therapy (RT), commonly used to treat benign and malignant brain tumors, can lead to cognitive impairments in domains not related to neuroanatomic structures direc

📍 James P. Wilmot Cancer Center at University of Rochester Medical Center — Rochester, New York

💵 Subjects will receive MRI scans at baseline, 6 months, and 12 months.

Dynamic Change and Immune Response to Nasopharyngeal Carriage and Acute Otitis Media Pathogens

The investigators seek to conduct a prospective, longitudinal study to identify the dynamic changes in nasopharyngeal (NP) colonization patterns and acute otitis media (AOM) etiolo

📍 Rochester General Hospital — Rochester, New York

A Phase 1 Trial of Intranasal Mumps Virus Vaccines in Healthy Adults

The purpose of this trial is to evaluate the safety and immunogenicity of CVM150 and CVM26. The trial will enroll up to 60 healthy participants.

📍 University Of Rochester Medical Center — Rochester, New York

Community Outreach for Palliative Engagement -- Parkinson Disease

The purpose of this study is to learn more about the effectiveness of palliative care training for community physicians and telemedicine support services for patients and carepartn

📍 University of Rochester Medical Center for Health + Technology — Rochester, New York

Health Protection and Promotion of Sign Language Interpreters Through Implementation of Total Worker Health®

Using mixed-methods and a clinical efficacy trial design, the overall objective of this study will employ implementation strategies to adapt and evaluate a previous integrated Tota

📍 University of Rochester Medical Center — Rochester, New York

Advancing Cervical Cancer Screening Through the Emergency Department - IIS

Cervical cancer screening in the Emergency Department

📍 University of Rochester — Rochester, New York

Efficacy of Methylene Blue Photodynamic Therapy for Treatment of Deep Tissue Abscesses

The objective of this Phase 2 study is to evaluate the efficacy of methylene blue photodynamic therapy (MB-PDT) performed at the time of percutaneous abscess drainage for disinfect

📍 Highland Hospital — Rochester, New York

💵 All subjects will receive standard of care image-guided percutaneous abscess drainage.

Multi-Modal Digital Monitoring of Disease Symptoms Huntington's Disease

The objective of the study is to validate the use of wearable sensors and digital health technologies for monitoring disease activity in Huntington's Disease (HD). Healthy subjects

📍 University of Rochester Medical Center — Rochester, New York

Deaf CBT-TS to Reduce Suicide Risk

The goal of this clinical trial is to learn if a short, Zoom-based intervention, Cognitive Behavioral Therapy for Treatment-Seeking for Deaf Individuals (Deaf CBT-TS) can change be

📍 University of Rochester Medical Center — Rochester, New York

💵 During study assessments, all subjects will receive suicide risk assessments using the Columbia-Suicide Severity Rating

Phase Resolved Functional Lung MRI and Oscillometry for the Observation of Healthy Lung Function

This study will examine the relationship of airways resistance measured by oscillometry with ventilation defects measured by Phase Resolved Functional Lung (PREFUL) MRI in healthy

📍 University of Rochester Medical Center — Rochester, New York

A Phase 2 Study of Methylene Blue Photodynamic Therapy for Treatment of Breast Abscesses

The objective of this Phase 2 study is to evaluate the efficacy of methylene blue photodynamic therapy (MB-PDT) performed at the time of percutaneous breast abscess drainage for di

📍 University of Rochester Medical Center — Rochester, New York

💵 All subjects will receive standard of care ultrasound-guided percutaneous breast abscess drainage.

The Villainous Vape: Advancing Vaping Prevention Among Adolescents Through a Comic Book

This is a randomized controlled trial to assess the feasibility, acceptability, and preliminary impact of The Villainous Vape, a vaping prevention comic book, among adolescents.

📍 University of Rochester Medical Center — Rochester, New York

Visual Perception in Schizophrenia

This study aims to identify novel markers of psychosis using electroencephalography (EEG).

📍 University of Rochester — Rochester, New York

Digital Measures for Clinical Trial Endpoints in Huntington's Disease

MEND-HD is a longitudinal study evaluating the feasibility of passive monitoring of gait and chorea in patients with HD and the meaningfulness of these outcomes for patients with H

📍 University of Rochester Medical Center — Rochester, New York

Evaluating How Well Different Types of Light-sensitive Cells in the Eye Contribute to Its Focusing Ability

In this experiment, subjects will view shapes on a screen with varying colors and be asked to focus their eyes on the shapes. The shapes will look as though they are jumping to ran

📍 Chester F. Carlson Center for Imaging Science — Rochester, New York

Effects of Chemotherapy on Cognitive Function in Breast Cancer Patients & Non-Cancer Control Subjects With Optional Sub-Study Research Brain MRI

Study is enrolling newly diagnosed breast cancer patients about to start chemotherapy and age-matched control participants. The investigator is trying to better understand the prev

📍 University of Rochester — Rochester, New York

Auditory EEG and Behavioral Assessments in Individuals With Rett Syndrome

This observational research study is designed to learn more about how the brain processes sound in individuals with Rett syndrome. Participants will complete a noninvasive electroe

📍 Center for Advanced Brain Imaging and Neurophysiology, University of Rochester Medical Center — Rochester, New York

Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes (START 2)

The aim of our study is to compare neonatal and maternal outcomes using different thresholds for the initiation and titration of pharmacotherapy for gestational diabetes (GDM). Our

📍 University of Rochester Medical Center — Rochester, New York

The Role of Brain Dopamine in Chronic Pain

Chronic pain is associated with plasticity in the brain limbic system composed mainly of the amygdala, hippocampus, ventral striatum, and cingulate cortex (ACC) /medial prefrontal

📍 University of Rochester Medical Center — Rochester, New York

💵 Additionally, all subjects are told that two of their 'win' trials would be randomly selected at the end of the experime

Impact of Increased Body Mass Index on Adolescent Fixed Orthodontic Treatment. A Prospective Longitudinal Study

The goal of this prospective observational study is to assess the influence of increased body mass index (BMI) on various oral health and orthodontic-related parameters in adolesce

📍 Eastman Institute for Oral Health, University of Rochester — Rochester, New York

Remote Assessments and Genetic Determinants of Myotonic Dystrophy

The goal of this observational study, conducted in participants' homes and requiring no travel to a study site, is to better understand disease variability in people with myotonic

📍 University of Rochester — Rochester, New York

💵 * Participants will receive a toolkit in the mail which includes all necessary equipment to participate in the study, in

Human Visual and Vestibular Motion Perception Study

The purpose this study is to measure sensitivity to visual and vestibular or balance motion. It is hoped that the results may help researchers better understand how aging and disea

📍 University of Rochester Medical Center — Rochester, New York

Families Moving Forward (FMF) Connect Pro for Mental Health Providers

The goal of this clinical trial is to test a new provider-assisted version of the caregiver Families Moving Forward (FMF) Connect app ("FMF Connect Pro") with mental health provide

📍 Mt. Hope Family Center — Rochester, New York

My Health Coach App RCT

The goal of this clinical trial is to learn if the My Health Coach app helps adults with fetal alcohol spectrum disorders (FASD). The main questions it aims to answer are: Does th

📍 University of Rochester — Rochester, New York

💵 Wait-list participants will receive the app after T3.

Myotonic Dystrophy and Facioscapulohumeral Muscular Dystrophy Registry

Myotonic dystrophy (DM) and facioscapulohumeral muscular dystrophy (FSHD) are inherited disorders characterized by progressive muscle weakness and loss of muscle tissue. The purpos

📍 University of Rochester Medical Center, Department of Neurology — Rochester, New York

Facilitating Lactation Through Optimized Workflows - Evaluating the Efficiency of Pumping Protocols and Cellular Mechanisms of Milk Production

The purpose of this study is to evaluate the effectiveness of two different breast pumping protocols in increasing milk production among lactating individuals diagnosed with primar

📍 URMC Breastfeeding & Lactation Clinic — Rochester, New York

Povidone Iodine Efficacy Study

This is a single center, randomized, double-blind, placebo-controlled Phase II clinical trial (RCT) to evaluate the efficacy of topical 10% Polyvinylpyrrolidone-Iodine (PVPI) to pr

📍 University of Rochester — Rochester, New York

Effect of Visual Retraining After Stroke

This project is intended to collect data using standard clinical tests and psychophysics to quantify the effect of visual cortical damage on the structure of the residual visual sy

📍 University of Rochester Medical Center — Rochester, New York

A Study to Evaluate the Impact of Mosunetuzumab Consolidation for Older Patients With Diffuse Large B-cell Lymphoma (DLBCL) Who Have Detectable Amounts of ctDNA (Circulating Tumor DNA) at the End of Treatment With Pola-R-mini-CHP

Older patients with diffuse large B- cell lymphoma (DLBCL) do not have the same rates of disease control as younger patients and are at risk for toxicity. Identifying which patient

📍 Wilmot Cancer Institute — Rochester, New York

💵 If older patients have detectable ctDNA in the blood at the end of six cycles of polatuzumab vedotin, rituximab and dose

Stand Up 2 HPV: Standing Orders to Improve HPV Vaccination

Each year in the U.S., ≥20,000 women and 14,000 men are affected by HPV-related cancers, including cervical and oropharyngeal cancer. However, in 2020, only 59% of U.S. adolescents

📍 University of Rochester Medical Center (URMC) — Rochester, New York

Mechanisms of Visual Restoration After Occipital Stroke

This project will collect brain imaging data to quantify the effects of early visual cortex damage and visual training interventions on the structure and function of the residual v

📍 University of Rochester — Rochester, New York