45 Paid Clinical Research Studies in Providence, Rhode Island

GEM: Impact of a Video Education Tool on Decisional Conflict Among Prenatal Patients

The goal of this randomized clinical trial is to assess the impact of a video educational tool on patient decisional conflict at the time when making a decision about prenatal gene

📍 Women and Infants — Providence, Rhode Island

Comparing Self-paced Versus Moderate Intensity Physical Activity Recommendation for Midlife Adults

We will randomly assign (blocked on Gender (female, male, other), body mass index (BMI; overweight \[25 \< BMI \< 30\]) or obese (30 \< BMI \<40) and pain status (chronic pain vs n

📍 Brown University — Providence, Rhode Island

💵 Following randomization, all participants will receive our theory-based PA promotion intervention to help them overcome

Using Telehealth to Address Alcohol Misuse in HIV Care

This project will test the effects of a telehealth counseling program on reducing alcohol use and improving HIV viral control among people with HIV who drink heavily. In total, 600

📍 Brown University — Providence, Rhode Island

Miro-randomized Trial for Optimizing a JITAI to Reduce Dietary Lapses in Obesity Treatment

This project targets dietary lapses (instances of nonadherence to dietary goals), a major cause of poor outcomes during behavioral obesity treatment, which is a recommended first-l

📍 Weight Control and Diabetes Research Center — Providence, Rhode Island

💵 All participants will receive a well-established 3-month online obesity treatment program, with 3 months of no-treatment

Program for Fully Understanding Eating and Lifestyle Change (FUEL)

This project seeks to better understand dietary lapses (instances of nonadherence to dietary goals), a major cause of poor outcomes during behavioral obesity treatment (BOT). Inves

📍 Weight Control and Diabetes Research Center — Providence, Rhode Island

💵 All participants will receive a well-established online BOT program for 12 months, with a 6-month maintenance period, fo

Positive Airway Pressure, Sleep Apnea, and the Placenta (PAP-SAP)

This study is testing the hypothesis of whether continuous positive airway pressure (CPAP) therapy improves placental histopathology and secretory function. The main aims of the st

📍 The Miriam Hospital — Providence, Rhode Island

💵 All subjects will receive small gift incentives such as baby-related items.

Targeting Weight and Shape Concern Among Women with High Body Weight

This study is a randomized controlled trial to evaluate the effect of an adapted version of the Body Project program among adult women of higher body weight who want to lose weight

📍 Weight Control and Diabetes Research Center — Providence, Rhode Island

Postoperative Restrictions for Patients Undergoing Minimally Invasive Gynecologic Procedures

The goal of this randomized controlled trial is to assess recovery in patients undergoing benign laparoscopic gynecologic surgery. The main question it aims to answer is: do libera

📍 Women and Infants Hospital — Providence, Rhode Island

Strategies for Improving Remote-based Weight Loss (PATH Trial)

The purpose of this study is to examine whether the addition of online yoga classes, compared to health and wellness classes, can improve the amount of weight loss produced from an

📍 The Miriam Hospital's Weight Control and Diabetes Research Center — Providence, Rhode Island

💵 Following the 3-month weight loss program participants will receive a 9-month weight loss maintenance program.

Predictors of De-novo Development of Obstructive Sleep Apnea in Pregnancy

This study seeks to understand the physical, physiologic and biologic features that predispose a woman to the development of obstructive sleep apnea once they are exposed to the ca

📍 The Miriam Hospital — Providence, Rhode Island

💵 Subjects will receive small gift incentives such as baby-related items.

Development of a Lifestyle Physical Activity Intervention to Reduce Risk for Perinatal Cannabis Use - RCT

The overall goal of this pilot study is to develop and preliminarily evaluate an LPA intervention designed to reduce cannabis use during pregnancy.

📍 Butler Hospital — Providence, Rhode Island

Basal Cell Carcinoma Chemoprevention Trial

This is an intent-to-treat, parallel design, multicenter randomized trial and the primary intervention is a double-blind comparison of Imiquimod (IMQ) vs. placebo cream for prevent

📍 Providence VA Medical Center, Providence, RI — Providence, Rhode Island

Stress Reactivity and Mother-Infant Cardiovascular Disease Risk

Prenatal Mindfulness training (MT) shows promise as a preventive intervention against hypertensive disorders of pregnancy (HDP) and may reduce risk for offspring cardiovascular dis

📍 Women's Medicine Collaborative, Lifespan — Providence, Rhode Island

Nurse-Led PrEP Initiation Among Incarcerated Individuals

PrEP is a medication that can help prevent the spread of HIV, but many who might benefit from PrEP do not take it. Individuals experiencing incarceration are interested in starting

📍 Rhode Island Hospital — Providence, Rhode Island

💵 Then, N = 60 participants will receive patient navigation support to help them link with PrEP care in the community and

Using Novel Behavioral Economic Measures to Characterize Dual Marijuana and Tobacco Use in Young Adults

The multi session experimental study aims to determine dual use patterns of marijuana and tobacco by assessing the impact of price and availability of marijuana and tobacco using a

📍 Brown University School of Public Health — Providence, Rhode Island

Assessing Interventions to Increase Tdap Acceptance for Non-birthing Partners in Pregnancy

The goal of this randomized control trial is to assess if prenatal vaccine education and in-office vaccination administration for non-birthing partners of pregnant patients increas

📍 Women and Infants Hospital — Providence, Rhode Island

💵 Participants will receive direct verbal and written education at the time of enrollment on cocooning and recommendation

Emergency Medicine Peer Outreach Worker Engagement for Recovery

This is an observational, prospective case-control study evaluating the effects of an emergency department community health worker-peer recovery specialist program (PCHW), the Subs

📍 Rhode Island Hospital — Providence, Rhode Island

Pilot Test of Five Weight Neutral Interventions to Improve Health Among Adults of Higher Body Weight

The purpose of this research study is to pilot test five different, group based and remotely delivered programs designed to support healthy eating and regular physical activity. Ea

📍 Weight Control and Diabetes Research Center — Providence, Rhode Island

Adolescent Stress and Substance Intervention Subsequent to Trauma

The long-term goal of this study is to address the adoption of the new trauma center requirement to establish best practices of screening for acute stress with an intervention to p

📍 Rhode Island Hospital — Providence, Rhode Island

The Impact of Acute Exercise in the Heat on Breast Milk Production and Composition in Lactating Women

This clinical trial aims to determine whether heat stress alters 24-hour breast milk production and composition following an acute bout of exercise in the heat among lactating wome

📍 Providence College — Providence, Rhode Island

💵 Participants will receive a water bottle to track their fluid intake, food log, an infant scale (Doran DS4500), breastmi

Targeting Alcohol-Opioid Co-Use Among Young Adults Using a Novel MHealth Intervention

The goal of this treatment development project is to develop and pilot an adaptive mobile health (mHealth) intervention that targets the co-use of alcohol and opioids in young adul

📍 Brown University Center for Alcohol and Addiction Studies — Providence, Rhode Island

The Dynamics of Representational Change Underlying Recall

The goal of this clinical trial is to examine how repeated memory retrieval changes visual representations in the brain in healthy adult participants. Specifically, the study aims

📍 Brown University Magnetic MRI Research Facility — Providence, Rhode Island

Prepping for The Talk: Helping Trusted Adults and Youth Talk About Sexual Health

The goal of this study is to help young people talk to trusted adults (including their parents, but also other adults) about sexual health more openly and honestly- including how t

📍 Rhode Island Hospital — Providence, Rhode Island

Early Diagnosis and Intervention for Fetal Malposition in Active Labor and Its Impact on Mode of Delivery

The goal of this randomized trial is to test if changing a person's position in labor can increase the chances of delivering their baby vaginally. Specifically, it aims to answer

📍 Women and Infant's Hospital of Rhode Island — Providence, Rhode Island

Intranasal Insulin for Treatment of Alcohol Use Disorder

This is a randomized controlled trial (RCT), within-subject, crossover, double-blind, placebo-controlled in non-treatment-seeking individuals with Alcohol Use Disorder (AUD) (N=40,

📍 Brown University — Providence, Rhode Island

💵 In a bar laboratory setting, randomized participants will receive a single dose of IN insulin (80IU) or an IN matched pl

A Sleep Hygiene Intervention to Improve Sleep Health in Urban, Latino Middle School Children

The main goal of this study is to evaluate the "SIESTA" intervention, a culturally and contextually tailored sleep hygiene intervention that has the potential to exert greater impr

📍 Rhode Island Hospital — Providence, Rhode Island

Cognitive Strategies for Weight Loss

The goal of this clinical trial is to compare weight change and other related outcomes associated with three different behavioral weight loss interventions (STANDARD Behavioral, PR

📍 Weight Control & Diabetes Research Center — Providence, Rhode Island

Evaluating an Intervention for Physician Burnout

The goals of this randomized controlled trial are 1) to test the efficacy of an app-based program in reducing physician burnout vs. no app (control) in 100 physicians; 2) to explor

📍 Brown University — Providence, Rhode Island

Combined Oral Motor Stimulation and Language on Preterm Infant Feeding

This is a randomized controlled trial to study an oromotor stimulation in combination with a reading curriculum in the NICU among preterm infants using oral muscle exercises, Langu

📍 Women & Infants NICU — Providence, Rhode Island

Improving Physical Activity Participation in Latinas With Mindfulness

In this study, the investigators are exploring how a mindfulness-based physical activity program can help improve exercise habits and overall health among 258 inactive Latina women

📍 Brown University — Providence, Rhode Island

💵 During the first 6 months, all participants will receive an exercise program that has previously been tested by our rese

Teen Health Choices & Wellness

The goal of this observational study is to learn more about changes in health, wellness, and substance-use behaviors as teenagers get older. Participants, ages 13 to 16, will be as

📍 Brown University School of Public Health — Providence, Rhode Island

Remote Approaches for Optimizing Weight Loss (Elevate Weight Loss Trial)

The purpose of this trial is to compare two delivery formats for weight loss (automated online program vs. group-based videoconference program) and to examine the added effect of i

📍 The Miriam Hospital's Weight Control and Diabetes Research Center — Providence, Rhode Island

Assessing the Short-Term Effects of Multi-Fiber Supplementation on Gut Health

This is a randomized, parallel-group interventional study evaluating the short-term gastrointestinal effects of a standardized multi-fiber supplement in healthy adults. Approximate

📍 Biomedical Center — Providence, Rhode Island

Connecting Loved Ones to Support and Empowering Recovery

Substance use disorders are highly prevalent. However, recovery from them is possible. The recovery process can benefit greatly from support from loved ones. Loved ones may need gu

📍 Rhode Island Hospital — Providence, Rhode Island

Cognitive Control & the Functional Organization of the Frontal Cortex

The goal of this basic experimental clinical trial is to understand the effect of multitasking practice on the structure of neural representations of tasks in the human lateral pre

📍 Metcalf Research Building, Brown University & MRI Research Facility, Brown University — Providence, Rhode Island

💵 Treatment will be administered during study sessions 6 through 8 during which subjects will receive either 3 sessions of

Self Neuro-modulation Therapy for Major Depressive Disorder (MDD) With Anhedonia

The purpose of this research is to learn more about a new treatment for individuals with Major Depressive Disorder (MDD) with heightened symptoms of anhedonia (i.e. loss of pleasur

📍 Butler Hospital — Providence, Rhode Island

💵 Participants will receive 20 NF sessions.

The Effect of Intrawound Vancomycin Powder on Surgical Site Infection in Inguinal Lymph Node Dissection

The study will be a pilot randomized control trial with a 1:1 patient randomization of vancomycin powder placement at the time of surgery (compared to no vancomycin placement) with

📍 Women and Infants Hospital — Providence, Rhode Island

Promoting Physical Activity and Healthy Eating in Latinas

The goal of this clinical trial is to learn if an Internet-based behavioral intervention can increase physical activity and improve diet quality among Latina adults. The main quest

📍 Brown University — Providence, Rhode Island

Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA

This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and

📍 Brown University — Providence, Rhode Island

Strong Families Start at Home/Familias Fuertes Comienzan en Casa

The goal of this clinical trial is to test the ability of a home-based parental nutrition intervention to improve diet quality in preschool aged children within low-income, Latinx/

📍 Brown University — Providence, Rhode Island

Mindfulness and Wearable Biosensors to Prevent Hypertensive Disorders of Pregnancy

The MINDBP study will enroll 90 pregnant women at risk for HDP across two sites (MCW and Brown) and randomize them to: (1) mindfulness training (MT) plus wearable biosensors, (2) M

📍 Brown University — Providence, Rhode Island

💵 MT participants will receive 8 weekly phone-based MT sessions plus two booster sessions at 1 and 2 months post-intervent

Feasibility and Acceptability of Mindful Self-Compassion Among Transgender and Nonbinary Young Adults

The goal of this single-arm feasibility study is to evaluate the feasibility and acceptability of an 8-week mindful self-compassion intervention and associated data-collection plan

📍 N/A-- All study activities being conducted virtually — Providence, Rhode Island

iPAWS: Improving Pain Management After Wisdom Tooth Extraction Surgery

This is a clinical trial that will evaluate the feasibility and acceptability of a virtual brief program for adolescents and young adults undergoing wisdom tooth extraction and the

📍 Brown University Center for Alcohol and Addiction Studies — Providence, Rhode Island

Video Intervention for Older Adults With Chronic Pain

Chronic musculoskeletal (MSK) pain, which includes spinal pain, osteoarthritis, and fibromyalgia, is a common and costly problem for older adults and is associated with decreased q

📍 Butler Hospital — Providence, Rhode Island

💵 All participants will receive an introductory pain education video.

Nicotine Regulation for Dual Users of E-cigarettes and Cigarettes

Cigarette smoking remains the leading cause of preventable morbidity and mortality in the US. Use of multiple tobacco products is becoming increasingly prevalent, with dual use of

📍 Brown University — Providence, Rhode Island