35 Paid Clinical Research Studies in Seattle, Washington

A Pediatric Trial of Genetically Modified Autologous T Cells Directed Against CD19 for Relapsed CD19+ Acute Lymphoblastic Leukemia

Patients with relapsed leukemia often develop resistance to chemotherapy. For this reason, we are attempting to use a patient's own T cells, which can be genetically modified to ex

📍 Seattle Children's Hospital — Seattle, Washington

💵 Several days later, the subject will receive an infusion of the CAR+ T cells.

Mobile Parkinson Observatory for Worldwide, Evidence-based Research (mPower)

The purpose of this study is to understand variation in the symptoms of Parkinson disease. This study uses an iPhone app to record these symptoms through questionnaires and sensors

📍 Sage Bionetworks — Seattle, Washington

IMAGINE: Pilot Trial of a Digital Group Intervention to Prevent Perinatal Depression

The goal of this clinical trial is to evaluate if a digital group intervention (named IMAGINE) can prevent depression in perinatal populations. The main questions it aims to answer

📍 Perinatal Support Washington — Seattle, Washington

Intradermal, Fractional Dose of HPV Vaccines:

This randomized phase IV trial compares fractional dose of bivalent HPV vaccine to fractional dose of nonavalent HPV vaccine among men and women aged 27-45 years in Seattle, Washin

📍 University of Washington Virology Research Clinic — Seattle, Washington

Immunogenicity of Fractional Dose of the HPV Vaccines

This randomized phase IV trial compares intramuscular and intradermal fractional dose of bivalent HPV vaccine to fractional dose of nonavalent HPV vaccine among men and women aged

📍 University of Washington Virology Research Clinic — Seattle, Washington

The Community Youth Development Study: A Test of Communities That Care

The Community Youth Development Study is an experimental test of the Communities That Care (CTC) prevention planning system. It has been designed to find out if communities that we

📍 University of Washington — Seattle, Washington

Yoga Effect on Quality of Life Study Among Patients with Idiopathic Pulmonary Fibrosis

This study will evaluate whether regular yoga exercises designed specifically for patients with Idiopathic Pulmonary Fibrosis is associated with any change in quality of life. Half

📍 University of Washington Medical Center — Seattle, Washington

💵 There is no cure for IPF other than lung transplantation, which only 1% of patients will receive.

Study to Assess the Effectiveness of a Heat Risk Reduction Decision Support Platform and the Barriers and Facilitators of Its Implementation With 30 US Local Health Department Sites

The goal of this clinical trial is to learn if an innovative online decision support tool (Chart) that provides localized health risk assessment for extreme heat at the census trac

📍 University of Washington — Seattle, Washington

Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or Incurable Hematologic Malignancies

This phase II trial tests the safety, side effects and how well group retreat psilocybin therapy works for the treatment of anxiety and depression in patients with solid tumors tha

📍 Fred Hutch/University of Washington Cancer Consortium — Seattle, Washington

💵 Patients may receive an additional "booster" dose 60-90 minutes after the initial dose based on their subjective report

Assessment of Heart Rate Measurement Accuracy for the PreemptiveAI SDK in Adults

The goal of this clinical trial is to assess the accuracy of the PreemptiveAI SDK to measure heart rate for adults as compared to an FDA-approved ground truth device. Participants

📍 Paul Allen Institute for Artificial Intelligence — Seattle, Washington

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

This is a phase I, open-label, non-randomized study that will enroll pediatric and young adult research participants with relapsed or refractory non-CNS solid tumors to evaluate th

📍 Seattle Children's Hospital — Seattle, Washington

💵 On Arm A of the study, research participants will receive EGFR-specific CAR T cells only.

Apolipoprotein E (APOE) Genotype Effects on Triglycerides and Blood Flow in the Human Brain

High fat feeding (HFF) increases the risk of Alzheimer's disease (AD) but individuals who carry the AD risk gene E4 paradoxically improve after acute HFF. The investigators propose

📍 University of Washington Medical Center — Seattle, Washington

💵 Screening Visit Procedures (at Seattle South Lake Union campus): Before the screening visit, participants will receive a

Washington State Driving Intervention Research Study

The goal of this clinical trial is to test the effect of hazard perception and attention maintenance training and testing on driving performance. Participants will be randomized in

📍 The Driver Training Group — Seattle, Washington

💵 Baseline hazard perception assessment will be performed first, and then participants will receive one of the four traini

Telephone Delivered Weight Loss, Nutrition, Exercise WeLNES Study

This phase III trial compares telephone delivered Acceptance and Commitment Therapy to standard behavioral therapy for improving weight loss in overweight or obese participants. Ac

📍 Fred Hutch/University of Washington Cancer Consortium — Seattle, Washington

PREVENT HPV -Related Cancers Trial

This study will serve as one of the first to develop and test the effectiveness of strategies to promote HPV vaccination among diverse rural parents and caregivers of children ages

📍 Sea Mar Community Health Centers — Seattle, Washington

Journey of Transformation Curriculum for Native American Youth

The investigators will conduct a waitlist control trial to test the efficacy of the Journey of Transformation-Native Youth Health Leadership Program (JOT) in terms of delaying or r

📍 University of Washington — Seattle, Washington

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

This is a phase I, open-label, non-randomized study that will enroll pediatric and young adult research participants with relapsed or refractory non-CNS solid tumors to evaluate th

📍 Seattle Children's Hospital — Seattle, Washington

💵 On Arm A of the study, research participants will receive B7H3-specific CAR T cells only.

Novel Methods for Implementing Measurement-Based Care for Youth in Low-resource Environments

This study will visit 4 community mental health clinics in Washington state and work with clinic staff to find out if staff are regularly evaluating clinical outcomes using questio

📍 KPWHRI — Seattle, Washington

Psorcast Mobile Study

The purpose of this study is to understand variation in the symptoms of psoriasis and psoriatic arthritis using simple, scalable smartphone-based measurements. This study uses an i

📍 Sage Bionetworks — Seattle, Washington

Engineered Neuroblastoma Cellular Immunotherapy (ENCIT)-01

Patients with recurrent or refractory neuroblastoma are resistance to conventional chemotherapy. For this reason, the investigators are attempting to use T cells obtained directly

📍 Seattle Children's Hospital — Seattle, Washington

💵 At least 48 hours after the completion of lymphodepletion, the subject will receive and infusion of CAR+ T cells at an a

Topical 10% Povidone-Iodine in Preventing White Spots

The goal of this clinical trial is to learn if topical application on the all surface of 10% Povidone Iodine (Povi-One) in healthy participants in transitional or permanent dentiti

📍 University of Washington, School of Dentistry Department of Orthodontics, 1959 NE Pacific St. Health Sciences Center — Seattle, Washington

Mobile Video Interpretation to Optimize Communication Across Language Barriers

Patients and families with limited English proficiency (LEP) and/or who use a language other than English for medical care (LOE) experience substantial barriers to communication in

📍 Seattle Children's — Seattle, Washington

💵 Patients will receive a gift card or cash for completing the survey.

Learning and Living With Wildfire Smoke

The proposed intervention in this Youth Participatory Action Research (YPAR) proposal will improve knowledge and awareness of the health impacts of air pollution exposure, will ele

📍 University of Washington — Seattle, Washington

Infusion of Expanded Cord Blood Cells in Addition to Single Cord Blood Transplant in Treating Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplastic Syndromes

This phase II trial studies how well donor umbilical cord blood transplant with ex-vivo expanded cord blood progenitor cells (dilanubicel) works in treating patients with blood can

📍 Fred Hutch/University of Washington Cancer Consortium — Seattle, Washington

💵 Before the transplant, patients will receive chemotherapy (fludarabine, cyclophosphamide and in some cases thiotepa) and

Implementation and Deliver of Lenacapavir for PrEP in a Community Pharmacy Setting

This is an open-label, single center study to evaluate implementation of a pharmacist-managed delivery of L4P in a community pharmacy setting and the impact of twice-yearly vs. qua

📍 Kelley-Ross Pharmacy — Seattle, Washington

Feasibility/Acceptability of a Brief Motivational Intervention for Frequent/High-Intensity Cannabis Use

The study aims to develop a novel brief motivational mobile health (mHealth) intervention for frequent and/or high-intensity cannabis use for non-collegiate young adults. A total o

📍 University of Washington — Seattle, Washington

CBT vs. Supportive Texts for PTSD & Hazardous Drinking (Project Better Study 2)

The study aims to test the efficacy of a CBT-enhanced text message intervention and a supportive text message intervention to reduce symptom burden in individuals with post-traumat

📍 University of Washington — Seattle, Washington

💵 For those in the intervention condition, participants will receive three text messages presenting a CBT skill followed b

VZV-specific Tissue Resident Memory T-cells After Shingrix Vaccination

To evaluate the effect of intramuscular RZV vaccine on VZV-specific skin TRM and circulating T-cells

📍 University of Washington Virology Research Clinic — Seattle, Washington

💵 All participants will receive the FDA-approved recombinant zoster (RZV) vaccine (Shingrix) given at the approved dose an

Motivating Campus Change Study

The study evaluates the relative merit of a multi-component PFI presented in the traditional simultaneous delivery (i.e., all components at once) versus a sequential format, wherei

📍 The Center for the Study of Health and Risk Behaviors — Seattle, Washington

Inherited and Environmental Risks Acting on Body Weight

The goal of this research is to investigate genetic and environmental factors that contribute to obesity through brain inflammation. The main questions are 1) if identical twins, w

📍 University of Washington — Seattle, Washington

Naive T Cell Deplete Grafts for GVHD Prevention in Non-Malignant Diseases

This phase II trial investigates how well a naive T cell depleted graft work for the reduction of graft versus host disease in patients with non-malignant diseases requiring hemato

📍 Seattle Children's Hospital — Seattle, Washington

💵 OUTLINE: Patients will receive CD34+ enriched CD45RA-depleted donor T-lymphocytes IV on day 0.

Evaluating a Shared Decision-making Intervention for Families About Firearm Storage

Investigators will conduct a randomized controlled trial assessing effectiveness of the Family Safety Check-In website on firearm storage practices. Prior to conducting the RCT, in

📍 Seattle Children's Hospital — Seattle, Washington

An Educational Intervention (Lung Toolkit) for Improving Knowledge About Lung Cancer and Screening Among American Indian and Alaskan Native Cigarette Smokers, Lung PATHS Trial

This clinical trial evaluates the acceptability and effectiveness of an educational intervention (Lung Toolkit) for improving knowledge about lung cancer and lung cancer screening

📍 Fred Hutch/University of Washington Cancer Consortium — Seattle, Washington

Adjuvant Therapeutic Cancer Vaccine (AST-201, pUMVC3-hIGFBP-2) in Patients With Advanced Ovarian Cancer

The purpose of this phase 2 study is to assess the efficacy and safety for adjuvant therapeutic cancer vaccine AST-201 (pUMVC3-hIGFBP-2) in patients with newly diagnosed homologous

📍 University of Washington — Seattle, Washington

💵 Patients will receive AST-201 with rhuGM-CSF(Colony Stimulating Factor) or placebo with rhuGM-CSF in combination with st

Tele-HOPE: A Telehealth Pharmacist Opioid Patient Education Pilot Study

This clinical trial will evaluate the feasibility, acceptability, and potential efficacy of a palliative care pharmacist-led group telehealth opioid education session for palliativ

📍 Fred Hutch/University of Washington Cancer Consortium — Seattle, Washington

💵 After attending the pharmacist education session, patients will receive a patient education handout summarizing the educ