Combination Chemotherapy, Radiation Therapy, and Bevacizumab in Treating Patients With Newly Diagnosed Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery (NCT00334815)

🧪 Interventions in This Study

• Bevacizumab (BIOLOGICAL)
• Cisplatin (DRUG)
• Docetaxel (DRUG)
• Etoposide (DRUG)
• Filgrastim (BIOLOGICAL)
• Pegfilgrastim (BIOLOGICAL)

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

1. Histologically or cytologically confirmed single, primary, bronchogenic, non-small cell lung cancer (NSCLC)
2. Newly diagnosed disease
3. Unresectable disease
4. No more than 1 parenchymal lesions on same or opposite sides of the lungs
5. Meets 1 of the following stage criteria:
6. Stage IIIA (N2) disease meeting the following criteria:
7. N2 mediastinal lymph nodes must be multiple and/or bulky on CT scan or x-ray so that the patient is not a candidate for induction chemotherapy or chemoradiotherapy followed by surgical resection
8. N2 status must be documented by ≥ 1 of the following methods:
9. Histologically or cytologically confirmed N2 disease by exploratory thoracotomy, thoracoscopy, mediastinoscopy, mediastinotomy, Chamberlain procedure, Wang needle biopsy (WNB), fine needle aspiration (FNA) under bronchoscopic or CT guidance, or any other method
10. Node positive by fludeoxyglucose-positron emission tomography (FDG-PET) scan
11. Nodes \> 3 cm on CT scan
12. Paralyzed left true vocal cord with separate left lung primary distinct from anterior-posterior window nodes on CT scan

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (61 Sites)

Showing the first 25 of 61 sites.

• Providence Hospital — Mobile, Alabama
• Saint Bernards Regional Medical Center — Jonesboro, Arkansas
• University of Arkansas for Medical Sciences — Little Rock, Arkansas
• Highlands Oncology Group - Rogers — Rogers, Arkansas
• USC / Norris Comprehensive Cancer Center — Los Angeles, California
• Fremont - Rideout Cancer Center — Marysville, California
• UC Irvine Health/Chao Family Comprehensive Cancer Center — Orange, California
• University of California Davis Comprehensive Cancer Center — Sacramento, California
• Providence Santa Rosa Memorial Hospital — Santa Rosa, California
• Gene Upshaw Memorial Tahoe Forest Cancer Center — Truckee, California
• Northbay Cancer Center — Vacaville, California
• Rocky Mountain Regional VA Medical Center — Aurora, Colorado
• UCHealth University of Colorado Hospital — Aurora, Colorado
• Denver Health Medical Center — Denver, Colorado
• Shaw Cancer Center — Edwards, Colorado
• Valley View Hospital Cancer Center — Glenwood Springs, Colorado
• Montrose Memorial Hospital — Montrose, Colorado
• Cancer Centers of Central Florida PA — Leesburg, Florida
• Lewis Cancer and Research Pavilion at Saint Joseph's/Candler — Savannah, Georgia
• Loyola University Medical Center — Maywood, Illinois
• Edward Hospital/Cancer Center — Naperville, Illinois
• HaysMed — Hays, Kansas
• Hutchinson Regional Medical Center — Hutchinson, Kansas
• University of Kansas Cancer Center — Kansas City, Kansas
• Olathe Cancer Center — Olathe, Kansas

💰 Cost, Insurance & Patient Rights

• 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
• Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
• Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

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💡 How to Participate

1. Check the checklist above to see if you may qualify.
2. Review the official NIH record below to find the coordinating site.
3. Ask about the visit schedule, what is covered at no cost, and any travel support.
4. Confirm with your own doctor before making a decision.