🏛️ Verified NIH Record • Updated 2026-03-11

Reduced Intensity Haploidentical BMT for High Risk Solid Tumors (NCT01804634)

A Phase II Trial of Reduced Intensity Conditioning and Partially HLA-mismatched (HLA-haploidentical) Related Donor Bone Marrow Transplantation for High-risk Solid Tumors

🟢 Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this study is to see if giving reduced intensity chemotherapy, haploidentical bone marrow, post-transplant cyclophosphamide and shortened duration tacrolimus is safe and feasible for patients with very high-risk solid tumors.

Who can join: Review the eligibility criteria below.

Location: The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins — Baltimore, Maryland

Age range: 1 Year to 50 Years

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (3 Sites)

  • The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins — Baltimore, Maryland
  • Albert Einstein College of Medicine, Children's Hospital at Montefiore — The Bronx, New York
  • New York Medical Center/ Maria Fareri Children's Hospital — Valhalla, New York

📞 Contact the Study Coordinator

Phone: (410) 502-4997

Email: hsymons2@jhmi.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
  • 💵 Compensation indicated: Growth factor support Patients will receive G-CSF (Filgrastim®) 5µg/kg/d SC or IV starting at Day 5 and continuing until the ANC\>1000/mm3 x 3days or two consecutive measurements over a three day ...

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗