Who is eligible for clinical trial NCT02230839?

Participants must meet the protocol's inclusion criteria for Insulin Resistance. The stated age range is 65 Years to 80 Years. Confirm all requirements with the study coordinator.

Does clinical trial NCT02230839 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2025-08-01

Muscle Insulin Resistance in Aging (Mirage) (NCT02230839)

Muscle Insulin Resistance In Aging

🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program Sponsor: AdventHealth Translational Research Institute

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this study is to provide information regarding potential factors underlying metabolic dysfunction, insulin resistance, and loss of muscle mass in aging muscle.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (8 items) and avoid the listed exclusions (8 items).

Location: Translational Research Institute for Metabolism and Diabetes — Orlando, Florida

Age range: 65 Years to 80 Years

🧪 Interventions in This Study

Exercise (BEHAVIORAL)
Energy Restriction-Induced Weight Loss (BEHAVIORAL)

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

65-80 years of age
Stable weight (No Gain/Loss of \>10 lbs in 6 months)
Sedentary (≤ 1 continuous exercise/week)
Non-smoker
BMI ≥ 30 kg/m2
Resting Blood Pressure ≤ 150 millimeters of mercury systolic and ≤ 95 millimeters of mercury diastolic
Note from Primary care physician/Cardiologist for exercise clearance if positive stress test symptoms were observed from exercise test
Must be willing to washout for 14 days from all diabetes medication and independent in self blood glucose monitoring during the washout periods (those with diabetes only)

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
Clinically significant cardiovascular disease including history of myocardial infarction, within the past year
Peripheral Vascular Disease
Hepatic, renal, muscular/neuromuscular, or active hematologic/oncologic disease
Clinically diminished pulse
Presence of bruits in lower extremities
Previous history of pulmonary emboli
Peripheral Neuropathy

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

Translational Research Institute for Metabolism and Diabetes — Orlando, Florida

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Insulin Resistance

Determinants of Insulin Sensitivity by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis — Houston, Texas
Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With Obesity — Bethesda, Maryland
Intramyocellular Fatty Acid Trafficking in Insulin Resistance States - Effects of Intestinal Delivery of Lipids — Rochester, Minnesota
Alpelisib Challenge Test (ACT) — New York, New York
Human Models of Selective Insulin Resistance: Pancreatic Clamp — New York, New York

Explore by condition: All Insulin Resistance clinical trials

💡 How to Participate

Check the checklist above to see if you may qualify.
Review the official NIH record below to find the coordinating site.
Ask about the visit schedule, what is covered at no cost, and any travel support.
Confirm with your own doctor before making a decision.

🏛️ View Official NIH Record ↗