Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery (NCT03184038)
Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery: A Phase II Study
🩺 Plain-English Summary (8th-Grade Level)
This phase II trial studies the neurological function in patients with multiple brain metastases undergoing stereotactic radiosurgery (SRS) or stereotactic body radiation therapy (SBRT). Stereotactic body radiation therapy uses special equipment to position a patient and deliver radiation to tumors with high precision. This method can kill tumor cells with fewer doses over a shorter period and cause less damage to normal tissue. Assessment of neurocognitive function may help show that SRS preserves neurological function in patients with multiple brain metastases better than SBRT.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (9 items) and avoid the listed exclusions (7 items).
Location: Jefferson Health New Jersey — Sewell, New Jersey
Age range: 18 Years
🧪 Interventions in This Study
- Cognitive Assessment (PROCEDURE)
- Stereotactic Radiosurgery (RADIATION)
- Stereotactic Body Radiation Therapy (RADIATION)
- Quality-of-Life Assessment (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Patient with diagnosis of glioma, or other World Health Organization (WHO) grade II - IV primary brain tumor
- Prior brain surgery =\< 14 days prior to enrollment
- Planned chemotherapy during radiosurgery
- Leptomeningeal metastases
- Intractable seizures while on adequate anticonvulsant therapy-more than 1 seizure per week for the past 2 months
- Pregnant women
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (2 Sites)
- Jefferson Health New Jersey — Sewell, New Jersey
- Sidney Kimmel Cancer Center at Thomas Jefferson University — Philadelphia, Pennsylvania
📞 Contact the Study Coordinator
Phone: (215) 955-6702
Email: wenyin.shi@jefferson.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Metastatic Malignant Neoplasm in the Brain
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- Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain Metastases — Phoenix, Arizona
- Neuropsychological Care for Maintaining Quality of Life After Radiation Therapy in Patients With Brain Metastases — Columbus, Ohio
- Arginine and Whole Brain Radiation Therapy for the Treatment of Patients With Brain Metastases — Atlanta, Georgia
- Stereotactic Radiosurgery Compared to Observation in Treating Patients With Brain Metastases — Houston, Texas
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.