Who is eligible for clinical trial NCT04109638?

Participants must meet the protocol's inclusion criteria for Knee Injuries. The stated age range is 18 Years. Confirm all requirements with the study coordinator.

Does clinical trial NCT04109638 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-01-20

Pulsed Electromagnetic Field (PEMF) Therapy for Post-operative Pain Following Orthopedic Surgery (NCT04109638)

A Pilot Prospective, Randomized, Placebo-Controlled Study to Evaluate the Efficacy of Pulsed Electromagnetic Field (PEMF) Therapy in Decreasing Post-Operative Pain Following Orthopedic Surgery

🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol Sponsor: Stanford University

🩺 Plain-English Summary (8th-Grade Level)

The primary objective of this study is to prospectively determine, at 10 days after orthopedic shoulder or knee surgery, if pulsed electromagnetic field (PEMF) therapy is beneficial in reducing patient-reported post-operative pain, as measured by visual analog scale (VAS). The amount of pain medication taken daily and the physical function outcome scores after surgery and PEMF treatment will also be measured.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (5 items) and avoid the listed exclusions (18 items).

Location: Stanford University — Redwood City, California

Age range: 18 Years

🧪 Interventions in This Study

Endonovo SofPulse (DEVICE)

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Subjects may be male or female greater or equal to 18 years of age (≥ 18) at the time of consent.
Subjects who will be having shoulder or knee surgery are permitted.
Subject must not have used NSAIDs for one (1) week prior to surgery. a. a. Low-dose aspirin (81 mg) is permitted.
Subject must be willing and able to participate in post-operative physical therapy exercises.
Subject must understand and be willing to sign the IRB-approved Informed Consent Document.

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
Subject has a known collagen disorder such as, but not limited to, osteogenesis imperfecta (OI) or Ehlers-Danlos syndrome (EDS).
Subject has a known inflammatory or autoimmune connective tissue disease such as, but not limited to, gout affecting the shoulder, scleroderma, SLE, rheumatoid disease, or calcific tendonitis of the shoulder.
Subject has a metabolic bone disease such as Paget's disease or osteomalacia as documented in the medical record.
Subject has a deltoid defect, deltoid palsy or any other pseudoparalysis.
Subject is diabetic.
Subject has HIV or hepatitis.
Subject has a diagnosis of fibromyalgia or other chronic pain syndrome.
Subject has shoulder or knee pain of unknown etiology.
Subject has had an active malignancy in the past 5 years OR has an active or on-going neoplastic disease, except for benign skin cancer(s).
Subject has undergone administration, within 30 days prior to surgery, of any type of corticosteroid (with the exception of asthma medications and ophthalmic medications), antineoplastic, immunostimulation or immunosuppressive agent.
Subject is septic, or has a local or systemic infection.

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

Stanford University — Redwood City, California

📞 Contact the Study Coordinator

Phone: (650) 723-0003

Email: mxiao@stanford.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

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Explore by condition: All Knee Injuries clinical trials

💡 How to Participate

Check the checklist above to see if you may qualify.
Contact the study coordinator using the phone/email above.
Ask about the visit schedule, what is covered at no cost, and any travel support.
Confirm with your own doctor before making a decision.

🏛️ View Official NIH Record ↗