🏛️ Verified NIH Record • Updated 2026-07-02

Mechanisms for Activation of Beige Adipose Tissue in Humans (NCT04666636)

🟢 Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Philip Kern

🩺 Plain-English Summary (8th-Grade Level)

Mirabegron (Myrbetriq®, Astellas) is a highly specific and well-tolerated ß3 agonist marketed for overactive bladder. This trial will assess the effects of mirabegron on glucose tolerance and adipose tissue in prediabetic patients

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (3 items) and avoid the listed exclusions (9 items).

Location: University of Kentucky — Lexington, Kentucky

Age range: 35 Years to 65 Years

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Usually NOT eligible if any of the following apply:

  • Exclusion Criteria:
  • diabetes
  • chronic use of anti-diabetic medication
  • acute or chronic inflammatory condition
  • unstable medical condition
  • cancer
  • renal insufficiency
  • any contraindication for Mirabegron
  • BMI \>45

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

  • University of Kentucky — Lexington, Kentucky

📞 Contact the Study Coordinator

Phone: (859) 218-1397

Email: zachary.leicht@uky.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All PreDiabetes clinical trials

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗