🏛️ Verified NIH Record • Updated 2025-10-30

Prospective Study of Pregnancy in Women With Cystic Fibrosis (NCT04828382)

A Prospective Study Evaluating Maternal and Fetal Outcomes in the Era of Modulators

🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: Amalia Magaret

🩺 Plain-English Summary (8th-Grade Level)

In this study, the investigators aim to evaluate changes in lung function in women with cystic fibrosis (CF) during pregnancy and for 2 years after pregnancy based on exposure to highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (1 items) and avoid the listed exclusions (1 items).

Location: University of Alabama at Birmingham — Birmingham, Alabama

Age range: 16 Years

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Usually NOT eligible if any of the following apply:

  • Exclusion Criteria:

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (40 Sites)

Showing the first 25 of 40 sites.

  • University of Alabama at Birmingham — Birmingham, Alabama
  • University of Arkansas for Medical Sciences — Little Rock, Arkansas
  • University of California San Diego — La Jolla, California
  • National Jewish Health — Denver, Colorado
  • University of Florida — Gainesville, Florida
  • Joe DiMaggio Children's Hospital — Hollywood, Florida
  • Emory University — Atlanta, Georgia
  • Saint Luke's Cystic Fibrosis Center of Idaho — Boise, Idaho
  • Indiana University Medical Center — Indianapolis, Indiana
  • University of Kansas Medical Center — Kansas City, Kansas
  • University of Kentucky — Lexington, Kentucky
  • Tulane University — New Orleans, Louisiana
  • John Hopkins Hospital — Baltimore, Maryland
  • Massachusetts General Hospital — Boston, Massachusetts
  • Boston Children's Hospital, Brigham & Women's Hospital — Boston, Massachusetts
  • University of Michigan Health System — Ann Arbor, Michigan
  • Helen DeVos Children's Hospital — Grand Rapids, Michigan
  • The Minnesota Cystic Fibrosis Center — Minneapolis, Minnesota
  • Washington University School of Medicine — St Louis, Missouri
  • University of Nebraska Medical Center — Omaha, Nebraska
  • The Cystic Fibrosis Center of Western New York — Buffalo, New York
  • Columbia University Cystic Fibrosis Program — New York, New York
  • University of Rochester Medical Center Strong Memorial — Rochester, New York
  • SUNY Upstate Medical University — Syracuse, New York
  • University of North Carolina at Chapel Hill — Chapel Hill, North Carolina

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗