Who is eligible for clinical trial NCT04899687?

Participants must meet the protocol's inclusion criteria for Obsessive-Compulsive Disorder. The stated age range is 18 Years to 65 Years. Confirm all requirements with the study coordinator.

Does clinical trial NCT04899687 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-05-18

Study of Dextromethorphan in OCD and Related Disorders (NCT04899687)

Fluoxetine/Dextromethorphan in Obsessive-Compulsive and Related Disorders: an Open-Label Crossover Pilot Study

🟢 Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Stanford University

🩺 Plain-English Summary (8th-Grade Level)

The purpose of the study is to assess the tolerability and efficacy of dextromethorphan in combination with fluoxetine for symptom relief in OCD and related disorders.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (3 items) and avoid the listed exclusions (6 items).

Location: Stanford University — Stanford, California

Age range: 18 Years to 65 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Diagnosis of obsessive-compulsive disorder (OCD), body dysmorphic disorder (BDD), illness anxiety disorder (IAD) or somatic symptom disorder (SSD)
Living within California
Capacity to provide informed consent

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
Current bipolar disorder or psychotic disorder
Active moderate or severe substance use disorder, lifetime severe substance use disorder
Pregnant or nursing women
Use of prescribed psychotropic medications other than fluoxetine for 2 weeks prior to study start
Having commenced OCD-targeted exposure and response-prevention (ExRP) psychotherapy within 2 months of study start

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

Stanford University — Stanford, California

📞 Contact the Study Coordinator

Phone: (650) 497-2578

Email: ocdresearch@stanford.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Obsessive-Compulsive Disorder

Towards Remission and Full Recovery From Obsessive-compulsive Disorder — Montreal, Quebec
Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD — New Haven, Connecticut
Feasibility, Clinical Effects, and Safety of Psilocybin-assisted Psychotherapy for Treatment-resistant OCD — Toronto, Ontario
Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2) — Stanford, California
Effects of Psilocybin in Obsessive Compulsive Disorder — Baltimore, Maryland

Explore by condition: All Obsessive-Compulsive Disorder clinical trials

💡 How to Participate

Check the checklist above to see if you may qualify.
Contact the study coordinator using the phone/email above.
Ask about the visit schedule, what is covered at no cost, and any travel support.
Confirm with your own doctor before making a decision.

🏛️ View Official NIH Record ↗