A Randomized Controlled Trial of Inhaled Tranexamic Acid for the Treatment of Pulmonary Hemorrhage in Cancer Patients (NCT05053867)

🧪 Interventions in This Study

• tranexamic acid (DRUG)

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

1. Age \> 18 years old
2. Have a diagnosed hematological malignancy
3. Are actively receiving mechanical ventilation
4. Have evidence of pulmonary hemorrhage as defined by either
5. Persistently bloody secretions upon endotracheal tube suctioning, or
6. Evidence of diffuse alveolar hemorrhage by bronchoscopic examination
7. Signed informed consent by patient or if the subject lacks decision-making capacity, the subject's legally authorized representative
8. 3.2 Exclusion Criteria Patients excluded from participation in the study if any of the following criteria are met:
9. Presence of a Do Not Resuscitate (DNR), no escalation of care or comfort care order at the time of screening
10. Expected survival \< 48 hours
11. Evidence of nasal or oral spillage likely to be the cause of bloody secretions
12. Patients requiring 100% FIO2

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

• M D Anderson Cancer Center — Houston, Texas

📞 Contact the Study Coordinator

Phone: (713) 745-5787

Email: nrathi@mdanderson.org

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

• 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
• Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
• Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Pulmonary Hemorrhage clinical trials

💡 How to Participate

1. Check the checklist above to see if you may qualify.
2. Contact the study coordinator using the phone/email above.
3. Ask about the visit schedule, what is covered at no cost, and any travel support.
4. Confirm with your own doctor before making a decision.