Post-Concussion Musculoskeletal Injury Risks (NCT05122728)
Post-Concussion Neuromuscular Function and Musculoskeletal Injury Risk
🩺 Plain-English Summary (8th-Grade Level)
Musculoskeletal injuries (MSKI) and traumatic brain injury (TBI) are the signature injuries of the ongoing military conflicts. MSKI affect 800,000 Service Members annually and TBI have impacted more than 350,000 in the past 19 years and account for 22% of all combat casualties. Concussion, a mild form of TBI, increases MSKI risk in physically active individuals, including Service Members. The overall goal of the study is to identify the neuromuscular control mechanisms that increase MSKI risk following concussion. It is hypothesized that concussed individuals will display abnormal neuromuscular function that increases MSKI risk, as compared to non-concussed controls. The study will employ a multi-center, prospective, case-matched control observational study to identify the differences in neuromuscular function following concussion that may contribute to increased MSKI risk. Once the neuromuscular control mechanisms that increase MSKI risk following concussion are identified, targeted risk mitigation strategies can be developed to reduce MSKI risk.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (13 items) and avoid the listed exclusions (16 items).
Location: University of Georgia — Athens, Georgia
Age range: 18 Years to 40 Years
🧪 Interventions in This Study
- Post-Concussion Neuromuscular Function and Musculoskeletal Injury Risk Assessment (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Post-Concussion Cohort AND Healthy Non-Concussed Cohort
- Unable to read or comprehend the English language.
- Admitted to the hospital following concussion.
- Sustained a concussion not related to physical activity participation (e.g., blast-related injury, fall from a ladder, motor vehicle accident).
- Loss of consciousness longer than 30 minutes.
- Alteration in consciousness longer than 24 hours.
- Post-traumatic amnesia lasting longer than 1 day.
- Glasgow Coma Scale below 13.
- Abnormal brain imaging findings.
- Sustained a concussion that took longer than 21 days for the individual to report as asymptomatic.
- A MSKI within the last 6 months that resulted in altered or missed physical activity for 3 or more consecutive days.
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (3 Sites)
- University of Georgia — Athens, Georgia
- Walter Reed National Military Medical Center — Bethesda, Maryland
- Womack Army Medical Center — Fort Bragg, North Carolina
📞 Contact the Study Coordinator
Phone: (301) 400-3477
Email: bradford.d.hendershot2.civ@health.mil
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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Explore by condition: All Musculoskeletal Injury clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.