🏛️ Verified NIH Record • Updated 2025-06-25

The Heartland Study (NCT05492708)

Children's Health in the Heartland Study

🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: Heartland Health Research Alliance

🩺 Plain-English Summary (8th-Grade Level)

The Heartland Study is a prospective, observational study that will enroll up to 2,600 pregnant participants across the Heartland States in the U.S.. The objective of the Heartland Study is to address major knowledge gaps concerning the health effects of herbicides on maternal and infant health. The study is being conducted to evaluate the associations between environmental exposures to herbicides during and after pregnancy and reproductive health outcomes. The study is measuring multiple biomarkers of herbicide exposure among pregnant Midwesterners and their partners to evaluate associations with pregnancy and childbirth outcomes, epigenetic biomarkers of exposure, and child development.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (2 items) and avoid the listed exclusions (3 items).

Location: Indiana University Medical Center — Indianapolis, Indiana

Age range: 18 Years

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Usually NOT eligible if any of the following apply:

  • Exclusion Criteria:
  • Participants who are not fluent in and/or do not fully understand, read, write, or speak the English language.
  • Other inability to provide informed consent to participate

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (4 Sites)

  • Indiana University Medical Center — Indianapolis, Indiana
  • University of Iowa Health Care — Iowa City, Iowa
  • Gundersen Health — La Crosse, Wisconsin
  • Marshfield Clinic — Marshfield, Wisconsin

📞 Contact the Study Coordinator

Phone: (317) 880-3961

Email: kamaflan@iu.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗