Effects of Exercise on Dystonia Pathophysiology (NCT05663840)
Progressive Resistance Exercise and Dystonia Pathophysiology.
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this research study is to investigate how the brain and motor behavior changes in individuals with dystonia in response to exercise training.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (5 items) and avoid the listed exclusions (8 items).
Location: University of Florida — Gainesville, Florida
Age range: 30 Years to 85 Years
🧪 Interventions in This Study
- Progressive resistance exercise (BEHAVIORAL)
- Standard of care (BEHAVIORAL)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Participating in an alternate structured exercise program, receiving regular physical or occupational therapy
- Have significant pain, spondylosis or active arthritis
- Fail the Physical Activity Readiness Questionnaire
- Have significant cognitive impairment
- Have implanted electrical device (eg, cardiac pacemaker or a DBS or a neurostimulator or metallic clip in their body, as necessitated by the risks of MRI or TMS
- Active seizure disorder; not be eligible for TMS and claustrophobic for MRI portion. As necessitated by the risks of MRI or TMS, patients who have any type of implanted electrical device (such as a cardiac pacemaker or a neurostimulator), or a certain type of metallic clip in their body (i.e., an aneurysm clip in the brain), active seizure disorder are not eligible for participation in the MRI or TMS portion of the study.
- Pregnancy tests will be carried out for each female subject of child bearing potential prior to the participation in the study and prior to each follow up visit (as indicated).
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- University of Florida — Gainesville, Florida
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Dystonia
- Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia — Boston, Massachusetts
- Vercise™ DBS Dystonia Prospective Study — Ghent,
- Deep Brain Stimulation Surgery for Focal Hand Dystonia — Bethesda, Maryland
- Studies of the Variable Phenotypic Presentations of Rapid-Onset Dystonia Parkinsonism and Other Movement Disorders — Miami, Florida
- Dystonia Genotype-Phenotype Correlation — Dallas, Texas
Explore by condition: All Dystonia clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.