🏛️ Verified NIH Record • Updated 2026-02-19

NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis (NCT05992883)

NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis: A Randomized, Controlled Trial

🟢 Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: Mayo Clinic

🩺 Plain-English Summary (8th-Grade Level)

The Researchers are trying to compare two different types of intraarticular injections (injection in the joint) for treating the symptoms of moderate to advanced basilar thumb arthritis. One injection is ketorolac (an NSAID) and the other is triamcinolone (a corticosteroid).

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (6 items) and avoid the listed exclusions (18 items).

Location: Mayo Clinic — Rochester, Minnesota

Age range: 40 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Usually NOT eligible if any of the following apply:

  • Exclusion Criteria:
  • • Known allergy to either of the treatment products
  • Patient's analgesic treatment regimen or other modalities of managing symptoms/pain associated with their hand pathology was modified within four weeks before trial inclusion
  • Symptomatic Scaphoid-trapezial arthritis present
  • Localized or systemic infection
  • Previous thumb surgery on study thumb
  • Previous thumb injury on study thumb
  • Patient with inflammatory arthritis (e.g., rheumatoid arthritis, psoriatic arthritis)
  • Severe and/or uncontrolled hypertension
  • De Quervain tendinopathy present
  • History of injection to the trapeziometacarpal joint on study thumb within the previous 6 weeks
  • Uncontrolled diabetes

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

  • Mayo Clinic — Rochester, Minnesota

📞 Contact the Study Coordinator

Phone: (507) 293-9765

Email: hobbs.lindsey@mayo.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗