Propranolol in Primary Progressive Aphasia (NCT06066710)
Trial of Propranolol in Older Adults With Primary Progressive Aphasia
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to find out how the language of people with Primary Progressive Aphasia is affected by Propranolol. Propranolol is not FDA approved for the treatment of Primary Progressive Aphasia. Propranolol is FDA approved for the treatment of heart conditions such as blood pressure. This research is being done because there are currently no drug treatment options for language impairments and anxiety often experienced by people with Primary Progressive Aphasia.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (3 items) and avoid the listed exclusions (15 items).
Location: University of Missouri-Columbia — Columbia, Missouri
Age range: 50 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- 1\. Unable to provide consent
- 2\. Taking alpha 2 agonists (clonidine and guanfacine)
- 3\. Other major psychological or neurological diagnosis
- 4\. Major head trauma that contributed to their condition
- 5\. Allergic reaction to adhesives
- 6\. Uncorrected vision/hearing impairments
- 7\. Diabetes
- 8\. Reactive airway disease
- 9\. Untreated hypothyroidism
- 10\. Bradyarrhythmia
- 11\. Unexplained syncope
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- University of Missouri-Columbia — Columbia, Missouri
📞 Contact the Study Coordinator
Phone: (573) 882-6081
Email: beversdorfd@health.missouri.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All Aphasia, Primary Progressive clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.