MitoQ Treatment of Claudication: Myofiber and Micro-vessel Pathology (NCT06409949)
🩺 Plain-English Summary (8th-Grade Level)
In our research, we are delving into whether taking MitoQ for six months can improve the symptoms and function of people diagnosed with peripheral artery disease, especially those who suffer from leg pain while walking, known as intermittent claudication. We will be checking if MitoQ helps people with claudication walk better, be more active every day, feel better about their lives, and if it enhances the health of their leg muscles.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (4 items) and avoid the listed exclusions (4 items).
Location: VA Medical Center — Omaha, Nebraska
Age range: 21 Years
🧪 Interventions in This Study
- Walking assessment (DIAGNOSTIC_TEST)
- QOL Survey (OTHER)
- Ankle pressure at rest and after stress (DIAGNOSTIC_TEST)
- Muscle Oxygen (DIAGNOSTIC_TEST)
- Serum MitoQ Level (DIAGNOSTIC_TEST)
- Needle Biopsy (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- rest pain or tissue loss due to PAD (Fontaine stage III and IV)
- acute lower extremity ischemic event
- walking capacity significantly and primarily limited by conditions other than claudication including leg (joint/musculoskeletal, neurologic) and systemic (heart, lung disease) pathology.
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- VA Medical Center — Omaha, Nebraska
📞 Contact the Study Coordinator
Phone: (402) 995-4171
Email: Holly.DeSpiegelaere@va.gov
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Peripheral Arterial Disease
- SELUTION4SFA Trial — Little Rock, Arkansas
- Use of Thermal Imaging Camera to Assess Perfusion Before and After Vascular Intervention — Beachwood, Ohio
- Shortwave Diathermy In-home Treatment for Indianapolis VA-only Patients Diagnosed With Peripheral Artery Disease and Peripheral Neuropathy — Indianapolis, Indiana
- Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease — Birmingham, Alabama
- SCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial Disease — Omaha, Nebraska
Explore by condition: All Peripheral Arterial Disease clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.