🏛️ Verified NIH Record • Updated 2026-08-18

SuperSaturated Oxygen Comprehensive Observational Registry (NCT06438315)

🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: TherOx

🩺 Plain-English Summary (8th-Grade Level)

The SuperSaturated Oxygen Comprehensive Observational Registry (SSCORE) registry, a prospectively designed observational study, aims to evaluate the clinical utility, infarct size reduction, and cost-effectiveness of SSO2 Therapy versus PCI alone among patients with anterior AMI in routine clinical practice.

Who can join: Review the eligibility criteria below.

Location: MemorialCare Orange Coast Medical Center — Fountain Valley, California

Age range: 18 Years to 80 Years

🧪 Interventions in This Study

  • KCCQ (OTHER)
  • Eq5D (OTHER)
  • cMRI (Subset of patients) (OTHER)

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (25 Sites)

  • MemorialCare Orange Coast Medical Center — Fountain Valley, California
  • UCSD Health La Jolla - Sulpizio Cardiovascular Center — La Jolla, California
  • MemorialCare Saddleback Medical Center — Laguna Hills, California
  • MemorialCare Long Beach Medical Center — Long Beach, California
  • Ronald Reagan UCLA Medical Center — Los Angeles, California
  • UCSD Hillcrest Medical Center — San Diego, California
  • UCLA Santa Monica Medical Center — Santa Monica, California
  • Baptist Health Baptist Hospital — Miami, Florida
  • NCH Baker Hospital — Naples, Florida
  • NCH North Naples — Naples, Florida
  • University of Chicago — Chicago, Illinois
  • Carle Health Methodist Hospital — Peoria, Illinois
  • Ascension Via Christi St Francis — Wichita, Kansas
  • Corewell Health Dearborn Hospital — Dearborn, Michigan
  • Mercy Hospital — Coon Rapids, Minnesota
  • Abbott Northwestern Hospital — Minneapolis, Minnesota
  • United Hospital — Saint Paul, Minnesota
  • RWJ- Jersey City Medical Center — Jersey City, New Jersey
  • Robert Wood Johnson University Hospital — New Brunswick, New Jersey
  • Newark Beth Israel Medical Center — Newark, New Jersey
  • North Shore University Hospital — Manhasset, New York
  • Long Island Jewish Hospital — Queens, New York
  • Charleston Area Medical Center — Charleston, West Virginia
  • St Mary's Medical Center — Huntington, West Virginia
  • Aurora St Luke's Medical Center — Milwaukee, Wisconsin

📞 Contact the Study Coordinator

Phone: (949) 300-2811

Email: sscore.zoll@zoll.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

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💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗