🏛️ Verified NIH Record • Updated 2026-03-16

A Trial to Evaluate the Efficacy and Safety of Sibeprenlimab Administered Subcutaneously in Participants With Sjögren's (NCT06928142)

A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy and Safety of Sibeprenlimab Administered Subcutaneously in Participants With Sjögren's

🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.

🩺 Plain-English Summary (8th-Grade Level)

This is a phase 2 study to evaluate the effects of sibeprenlimab 400 mg administered subcutaneously (SC) every 4 (Q4) weeks as an add-on to background treatment in participants with Sjögren's disease.

Who can join: Review the eligibility criteria below.

Location: Medvin Clinical Research - Riverside — Riverside, California

Age range: 18 Years to 75 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (64 Sites)

Showing the first 25 of 64 sites.

  • Medvin Clinical Research - Riverside — Riverside, California
  • Medvin Clinical Research - Tujunga — Tujunga, California
  • Bay Area Arthritis and Osteoporosis — Brandon, Florida
  • Clinical Research of West Florida Inc — Clearwater, Florida
  • GNP Research - Florida — Cooper City, Florida
  • Vantage Clinical Trials - Tampa - ClinEdge - PPDS — Tampa, Florida
  • OrthoIllinois, LTD — Rockford, Illinois
  • Arnold Arthritis and Rheumatology — Skokie, Illinois
  • Ochsner Clinic Foundation — Baton Rouge, Louisiana
  • Tufts University School of Dental Medicine — Boston, Massachusetts
  • Albuquerque Center for Rheumatology — Albuquerque, New Mexico
  • Bradenton Research Center Inc — The Bronx, New York
  • DJL Clinical Research PLLC — Charlotte, North Carolina
  • STAT Research — Vandalia, Ohio
  • Allen Arthritis — Allen, Texas
  • Tekton Research, LLC — Austin, Texas
  • Advanced Rheumatology of Houston — Houston, Texas
  • Accurate Clinical Research - Houston — Houston, Texas
  • Accurate Clinical Management, LLC — Katy, Texas
  • R & H Clinical Research — Katy, Texas
  • Consultorios Médicos Dr. Doreski - Fundacion Respirar - PPDS — Ciudad Autónoma de Buenos Aires, Buenos Aires
  • Instituto CER S.A. — Quilmes, Buenos Aires
  • Instituto Médico de la Fundación Estudios Clínicos — Rosario, Santa Fe Province
  • Clínica Mayo de U.M.C.B. S.R.L — San Miguel de Tucumán, Tucumán Province
  • Centro de Investigaciones Médicas Tucumán - PPDS — San Miguel de Tucumán, Tucumán Province

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Sjogren Disease clinical trials

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗