Effect of Watermelon on Cardiometabolic Health (NCT07006636)
Effect of Watermelon Consumption on Cardiometabolic Health and Whole-Body Antioxidant Capacity
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to determine whether consumption of 355 ml of watermelon juice will: 1. improve cardiovascular and overall metabolic health markers like blood pressure, heart rate, stiffness/flexibility of arteries (blood vessels), blood sugar, cholesterol), and gut hormones 2. contribute to the body's ability to protect itself from the potential cell damage caused by harmful chemical compounds (produced when skin is exposed to ultraviolet (UV) B light, for example). This will be evaluated by measuring how resistant skin is to the damage from UVB light exposure, as well as several markers of bodily stress blood and urine. This will be determined immediately after consuming the juice (to evaluate the effects the juice has on health right away), as well as after 4 weeks of daily juice consumption (to evaluate the effects the juice has on health when consumed consistently over time).
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (11 items) and avoid the listed exclusions (16 items).
Location: UCLA Center for Human Nutrition — Los Angeles, California
🧪 Interventions in This Study
- Watermelon Juice + liquid meal test at baseline (OTHER)
- Sweetened placebo beverage +liquid meal test at baseline (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Non-English speaker
- Vegetarian/vegan
- Known watermelon allergy
- Skin-related prescription medication, supplements, or non-prescription cosmeceutical agents
- Initiation of topical or oral prescription steroids and/or anti-inflammatory medications within 30 days prior to study enrollment
- Excessive exposure to either natural or artificial sunlight. Exposure to sunlight will be evaluated using Fitzpatrick Skin Type test score. Individuals receiving scores higher than the upper cutoff of the proposed range for the specific skin type will be excluded
- Screening laboratory values outside of the normal range that is considered clinically significant for study participation by the investigator
- Documented chronic disease, including diabetes, renal or liver diseases, metabolic syndrome, active cancer, MI or stroke, history of gastric bypass or GI disease (e.g., Crohn's disease, IBD, diverticulosis, diverticulitis, etc.)
- Taking medications or supplements known to affect metabolism or gut microbiota composition (antibiotics within the past 3 months, probiotics, fiber, etc.), unless willing to stop for the study duration
- Taking exogenous hormones (e.g., hormone replacement therapy)
- Recent weight fluctuations (\>10% in the last 6 months)
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- UCLA Center for Human Nutrition — Los Angeles, California
📞 Contact the Study Coordinator
Phone: (310) 206-8292
Email: tdiacova@mednet.ucla.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Cardiometabolic Health Indicators
- Behavioral Economic Attributes of Recreation — Chicago, Illinois
- Mango Intake and Gut and Cardiometabolic Health in Hispanic/Latino Adolescents — Davis, California
Explore by condition: All Cardiometabolic Health Indicators clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.