A Study of Herbal Supplements in Cancer Survivors With Constipation (NCT07091084)

🧪 Interventions in This Study

• MZRW (DIETARY_SUPPLEMENT)

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

1. Age 18 years or greater;
2. A diagnosis of cancer with no restrictions placed on type of cancer or stage;
3. Completed surgery, chemotherapy, immunotherapy, and/or radiotherapy, or an investigational therapy at least one month prior to study initiation. Patients on stable doses of hormone therapy or targeted therapies will not be excluded;
4. Karnofsky functional score of ≥ 60;
5. Cancer survivors who have met the Rome IV criteria (Table 3) of the symptoms of functional constipation which must include two or more of the following:
6. Straining more than 25% of defecations.
7. Lumpy or hard stools (7-point Bristol stool scale 1 or 2) more than 25% of defecations.
8. Sensation of incomplete evacuation more than one-fourth (25%) of defecations.
9. Sensation of anorectal obstruction/blockage more than one-fourth (25%) of defecations.
10. Manual maneuvers to facilitate more than one-fourth (25%) of defecations.
11. Fewer than three spontaneous bowel movements per week.
12. Loose stools are rarely present without the use of laxatives.

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (7 Sites)

• Memorial Sloan Kettering Basking Ridge (All Protocol Activities) — Basking Ridge, New Jersey
• Memorial Sloan Kettering Monmouth (All Protocol Activities) — Middletown, New Jersey
• Memorial Sloan Kettering Bergen (All Protocol Activities) — Montvale, New Jersey
• Memorial Sloan Kettering Suffolk- Commack (All Protocol Activities) — Commack, New York
• Memorial Sloan Kettering Westchester (All Protocol Activities) — Harrison, New York
• Memorial Sloan Kettering Cancer Center (All Protocol Activities) — New York, New York
• Memorial Sloan Kettering Nassau (All Protocol Activities) — Rockville Centre, New York

📞 Contact the Study Coordinator

Phone: (646) 608-8552

Email: maoj@mskcc.org

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

• 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
• Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
• Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Constipation

• Optimization of Postoperative Bowel Habits — Winston-Salem, North Carolina
• Use of a Squatting Assist Device in Patients With Constipation — Rochester, Minnesota
• Radicle GI HealthTM VNB: A Study Assessing the Impact of Health and Wellness Products on Constipation and Related Health Outcomes — Del Mar, California
• Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flush Regimen — Carmel, Indiana
• A Study of Microbiome Transplantation for the Treatment of Constipation and/or Significant Bloating in Patients With Systemic Sclerosis — Houston, Texas

Explore by condition: All Constipation clinical trials

💡 How to Participate

1. Check the checklist above to see if you may qualify.
2. Contact the study coordinator using the phone/email above.
3. Ask about the visit schedule, what is covered at no cost, and any travel support.
4. Confirm with your own doctor before making a decision.