Evaluation of Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN) (NCT07204275)
A Phase 2b/3 Adaptive, Randomized, Active-controlled Study Evaluating the Efficacy, Safety, and Tolerability of Povetacicept Versus Calcineurin Inhibitor in the Treatment of Primary Membranous Nephropathy
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to evaluate the efficacy, safety, and tolerability of povetacicept in participants with primary membranous nephropathy (pMN).
Who can join: Review the eligibility criteria below.
Location: Renal Associates — Montgomery, Alabama
Age range: 18 Years to 75 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (111 Sites)
Showing the first 25 of 111 sites.
- Renal Associates — Montgomery, Alabama
- Southwest Kidney Institute, PLC (SKI) - Surprise — Surprise, Arizona
- Academic Medical Research Institute (AMRI) — Los Angeles, California
- Valiance Clinical Research - Internal Medicine — Tarzana, California
- Western Nephrology & Metabolic Bone Disease PC — Arvada, Colorado
- Bioresearch Partner — Miami, Florida
- CTR Oakwater, LLC — Orlando, Florida
- Clinical Site Partners, LLC - Orlando — Winter Park, Florida
- DaVita Clinical Research Columbus — Columbus, Georgia
- Georgia Nephrology — Lawrenceville, Georgia
- CARE Institute-Boise Kidney — Boise, Idaho
- NANI Research — Hinsdale, Illinois
- DaVita Clinical Research Edina — Edina, Minnesota
- St. Clair Nephrology Research — Roseville, Missouri
- Kidney Specialists of Southern Nevada — Las Vegas, Nevada
- NYU Medical Center — New York, New York
- Carolina Nephrology Greenville — Greenville, South Carolina
- Carolina Nephrology, PA — Spartanburg, South Carolina
- El Paso Kidney Specialists — El Paso, Texas
- Provecta Research Network — Houston, Texas
- DaVita Clinical Research Houston — Houston, Texas
- Davita Clinical Research San Antonio — San Antonio, Texas
- Utah Kidney Research — Salt Lake City, Utah
- Milwaukee Neprologists, SC — Wauwatosa, Wisconsin
- Monash Medical Centre — Clayton,
📞 Contact the Study Coordinator
Phone: 001-617-341-6777
Email: medicalinfo@vrtx.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Primary Membranous Nephropathy
- A Study to Examine the Efficacy and Safety of Zanubrutinib Given to Adults With Primary Membranous Nephropathy — Granada Hills, California
- Study of ALXN1920 in Adult Participants With Primary Membranous Nephropathy (PMN) — Loma Linda, California
- A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Primary Membranous Nephropathy (PMN) — Huntsville, Alabama
- A Phase 2 Study of Budoprutug in Subjects With Primary Membranous Nephropathy — Denver, Colorado
- A Study Evaluating the Efficacy and Safety of Obinutuzumab in Participants With Primary Membranous Nephropathy — San Francisco, California
Explore by condition: All Primary Membranous Nephropathy clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.