A Study of Multiparametric Ultrasound Imaging Methods (NCT07270237)

🧪 Interventions in This Study

• Multiparametric ultrasound (mpUS) imaging (DIAGNOSTIC_TEST)

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

1. Cohort 1 - Feasibility of multiparametric endoscopic ultrasound (mpEUS) imaging of patients at high-risk for pancreatic cancer: Patient Group: those having standard endoscopic ultrasounds because they are at high risk of pancreatic cancer Participants enrolled into the Memorial Sloan Kettering Cancer Center Pancreatic Registry protocol (IRB#: 02-102) will be eligible for this study. Specifically, related individuals without pancreatic cancer who are at-risk for developing pancreatic cancer and meet all of the following criteria (family health history will be self-reported):
2. 10 years younger than the earliest pancreatic cancer diagnosis in the family
3. Be at least 50 years old
4. Be at least 40 years old if diagnosed with FAMMM syndrome (CDKN2A/p16) or Hereditary Pancreatitis (PRSS1, SPINK1/PST1, CTRC, CPA1 or other candidate hereditary pancreatitis genes)
5. Be at least 35 years old if diagnosed with Peutz-Jeghers syndrome (STK11 aka LKB1)
6. Not pregnant and not Nursing
7. Relatives at least 21 years old with other high-risk clinical criteria that warrants pancreatic cancer surveillance or follow-up as determined by the project leader (Dr. Vineet Rolston)
8. Must agree to be contacted for follow-up
9. Must satisfy at least one of the following 4 criteria:
10. Have at least two affected relatives who are a first-degree relative to each other, of whom at least one is a first degree relative to the individual OR have at least two affected first-degree relatives on the same side of the family.
11. Have at least one first- or second-degree affected relative and have germline genetic test results that confirm a likely pathogenic or pathogenic variant in at least one of the following genes:
12. APC (Familial Adenomatous Polyposis (FAP) and Attenuated FAP syndrome

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (7 Sites)

• Memorial Sloan Kettering Basking Ridge (Consent Only) — Basking Ridge, New Jersey
• Memorial Sloan Kettering Monmouth (Consent Only) — Middletown, New Jersey
• Memorial Sloan Kettering Bergen (Consent Only) — Montvale, New Jersey
• Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities) — Commack, New York
• Memorial Sloan Kettering Westchester (Consent Only) — Harrison, New York
• Memorial Sloan Kettering Cancer Center (All Protocol Activities) — New York, New York
• Memorial Sloan Kettering Nassau (Consent Only) — Uniondale, New York

📞 Contact the Study Coordinator

Phone: (646) 608-8284

Email: burgesm1@mskcc.org

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

• 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
• Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
• Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Pancreatic Cancer

• Alpha Radiation Emitters (DaRT) With Chemotherapy for the Treatment of Locally Advanced and Metastatic Pancreatic Cancer — Gilbert, Arizona
• Safety and Efficacy of Endoscopic Ultrasound (EUS) Guided Radiofrequency Ablation (RFA) in the Treatment of Pancreatic Lesions — Houston, Texas
• Evaluating Obesity-Mediated Mechanisms of Pancreatic Carcinogenesis in Minority Populations — Tampa, Florida
• A Study of the Life Changes Experienced by Patients With Pancreatic Cancer — New York, New York
• Radiotherapy in Combination With TTI-101 in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma — Aurora, Colorado

Explore by condition: All Pancreatic Cancer clinical trials

💡 How to Participate

1. Check the checklist above to see if you may qualify.
2. Contact the study coordinator using the phone/email above.
3. Ask about the visit schedule, what is covered at no cost, and any travel support.
4. Confirm with your own doctor before making a decision.