Opioid-Sparing Joint Replacement (NCT07348627)
Opioid-Sparing Joint Replacement - Single Site Randomized Control Trial
🩺 Plain-English Summary (8th-Grade Level)
The goal of this clinical trial is to evaluate whether an opioid-sparing postoperative pain regimen can reduce opioid consumption and maintain effective pain control in adults undergoing anterior total hip arthroplasty for osteoarthritis. The main questions it aims to answer are: * Does an opioid-limited regimen result in lower postoperative opioid use compared with a standard opioid prescription? * Does the opioid-limited regimen provide comparable or improved postoperative pain control and patient satisfaction?
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (4 items) and avoid the listed exclusions (15 items).
Location: Emory University Orthopedics and Spine Hospital — Atlanta, Georgia
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Concurrent significant injuries to other bones or organs
- Local infection at or near the surgical site
- Preoperative opioid use within 4 weeks prior to surgery
- History of severe heart disease (NYHA Class II or higher), renal failure, or liver dysfunction
- Chronic liver disease
- Neurological or psychiatric conditions that may influence pain perception
- Pregnancy
- History of alcohol or medication abuse
- Inability to take NSAIDs
- Use of postoperative DVT prophylaxis other than aspirin 81 mg twice daily
- Diabetes mellitus with HbA1c \> 8.0%
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- Emory University Orthopedics and Spine Hospital — Atlanta, Georgia
📞 Contact the Study Coordinator
Phone: (404) 778-3350
Email: ajay.premkumar@emory.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.