Who is eligible for clinical trial NCT07365514?

Participants must meet the protocol's inclusion criteria for Postmenopausal Osteoporosis. The stated age range is 45 Years to 70 Years. Confirm all requirements with the study coordinator.

Does clinical trial NCT07365514 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-07-21

Blackcurrants Modify Gut Microbiota and Reduce Osteoporosis Risk in Postmenopausal Females (NCT07365514)

Blackcurrants Mitigate Postmenopausal Bone Loss Through Gut Microbiota-Bone Axis: A Randomized Clinical Trial Coupled With a Multi-Omics Approach to Inform Precision Nutrition

🟢 Recruiting Phase1 💊 Investigational Drug / Biologic Sponsor: University of Connecticut

🩺 Plain-English Summary (8th-Grade Level)

The goal of this clinical trial is to evaluate the effects of blackcurrant (BC) supplementation on changes in bone density and gut microbiome composition in postmenopausal females.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (7 items) and avoid the listed exclusions (12 items).

Location: University of Connecticut, Department of Nutritional Sciences — Storrs, Connecticut

Age range: 45 Years to 70 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

postmenopausal (defined as no more than 10 years since final menstrual cycle) females aged 45-70 years
not on hormone replacement therapy for at least one year before initiation of the study
maintaining normal exercise level (\< 7 hours/week) and willing to avoid exercise for 24 hours prior to blood and stool sampling
willing to ingest a dietary blackcurrant supplement or placebo (up to 1,176 mg/day, three 392mg capsules)
willing to avoid other dietary supplements for the duration of the study
willing to avoid intake of foods extremely rich in anthocyanins and fermented dairy products containing viable Bifidobacteria or Lactobacilli
willing to have three blood draws, three stool collections, and three bone scans

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
history of cardiovascular disease, osteoporosis, metabolic bone disease, cancer, diabetes mellitus, arthritis, or other chronic inflammatory diseases
current smokers
taking prescription medications known to alter bone and calcium metabolism
taking anabolic agents such as parathyroid hormone or growth hormone, or steroid within 3 months before the start of the study
taking medications that alter bleeding (such as antiplatelets or anticoagulants) or those with a bleeding disorder
alcohol consumption exceeding 2 drinks/day (approximately 14g of ethanol per drink) or a total of 12/week
those with planned surgery during the study period or within 2 weeks of ending the intervention
those with sensitivities or allergies to any of the ingredients for the placebo (rice powder)
planning a procedure that includes iodine, barium or nuclear medicine isotopes within the study period
UConn students and/or employees who any key personnel teach or who report to any key personnel
study key personnel, partners of key personnel, or dependents/relatives of any key personnel

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

University of Connecticut, Department of Nutritional Sciences — Storrs, Connecticut

📞 Contact the Study Coordinator

Phone: (860) 486-6275

Email: ock.chun@uconn.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

💡 How to Participate

Check the checklist above to see if you may qualify.
Contact the study coordinator using the phone/email above.
Ask about the visit schedule, what is covered at no cost, and any travel support.
Confirm with your own doctor before making a decision.

🏛️ View Official NIH Record ↗