Buprenorphine for Analgesia in Older Adults With Acute Fractures in the Emergency Department (NCT07430345)
Buprenorphine for Analgesia in Older Adults With Acute Fractures in the Emergency Department: a Randomized Controlled Study
🩺 Plain-English Summary (8th-Grade Level)
The goal of this clinical trial is to learn if buprenorphine can treat pain in older adults who have broken bones. The main questions it aims to answer are: Is buprenorphine as effective as opioids to treat pain? Are there less side effects with buprenorphine? Researchers will compare buprenorphine and hydromorphone to see if there are differences in pain control and side effects. Participants will be given one of the two study drugs after breaking a bone and asked about their pain scores and side effects for the next 48 hours.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (6 items) and avoid the listed exclusions (6 items).
Location: Cooper University Hospital — Camden, New Jersey
Age range: 65 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Prior history of opioid use disorder
- Participants taking chronic opioid therapy (defined as opioids taken during the past month)
- Allergy to study medications
- Hemodynamic instability requiring immediate resuscitation
- Inability to consent and absence of surrogate decisionmaker
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- Cooper University Hospital — Camden, New Jersey
📞 Contact the Study Coordinator
Phone: (856) 342-2627
Email: selman-katherine@cooperhealth.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Fracture
- The PREVENT Trial: a Pragmatic Cluster Randomized Controlled Trial of a Multifaceted Fracture Prevention Model for Long-term Care — Hamilton, Ontario
- Intranasal Dexmedetomidine Plus Ketamine for Procedural Sedation — Edmonton, Alberta
- Pediatric Orthopaedic Implant Safety & Efficacy — Vancouver, British Columbia
- Cannabidiol After Multi-Trauma for Pain and Opioid Therapy — Montreal, Quebec
Explore by condition: All Fracture clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.