Remote Ischemic Conditioning for PwSCI (NCT07488793)
Remote Ischemic Conditioning Intervention to Enhance the Cardiometabolic Health of Persons With SCI
🩺 Plain-English Summary (8th-Grade Level)
The long-term goal of this project is to improve the overall cardiometabolic health of persons with spinal cord injury (SCI). This pilot study will test the feasibility and acceptability of remote ischemic conditioning implemented in a home setting by persons with SCI and collect cardiometabolic health outcomes to inform appropriate outcomes for a future larger trial. Researchers will compare, RIC high dose using standard blood pressure cuff to RIC high dose using automated blood flow restriction cuff to RIC low dose using standard blood pressure cuff, to determine cardiometabolic health improvements amongst groups. Participants will: Complete an initial 2-day assessment, participate in a 6-week intervention using remote ischemic conditioning (RIC) within their home, complete a 2-day post assessment.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (8 items) and avoid the listed exclusions (18 items).
Location: Washington University School of Medicine — St Louis, Missouri
Age range: 18 Years
🧪 Interventions in This Study
- RIC high-dose standard blood pressure cuff (BEHAVIORAL)
- RIC high-dose automated blood flow restriction cuff (BEHAVIORAL)
- RIC low-dose standard blood pressure cuff (BEHAVIORAL)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Medically unstable
- Have had a heart-related condition within the past year
- Have had a blood clot in the past year
- Have a stage 3 or 4 pressure injury
- Have taken blood thinners in the past year
- Have had surgery in the past year
- Have uncontrolled hypertension
- Have peripheral artery disease
- Have Complex Regional Pain Syndrome (CRPS) in both arms
- Have had nerve or tendon transfers in the arms in the past year
- Have lymphedema in the arms
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- Washington University School of Medicine — St Louis, Missouri
📞 Contact the Study Coordinator
Phone: (314) 286-1659
Email: morgank@wustl.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Spinal Cord Injuries
- Outcomes Post Treatment: Impact on Motor Impairment of Sleep Efficiency in SCI (OPTIMISE SCI Trial) — Toronto, Ontario
- Use of Point-of-care Neuro-sacral Electrophysiology Following Spinal Cord Injury — Montreal, Quebec
- Activity-Based Therapy and Transcutaneous Spinal Cord Stimulation After Spinal Cord Injury (ABT-TCSCS) — Toronto, Ontario
- Restoring Motor and Sensory Hand Function in Tetraplegia Using a Neural Bypass System — Manhasset, New York
- Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain — San Francisco, California
Explore by condition: All Spinal Cord Injuries clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.