Adding Dexmedetomidine or Clonidine to Spinal Anesthesia for Cesarean Delivery (NCT07567495)
🩺 Plain-English Summary (8th-Grade Level)
This study will examine whether addition of dexmedetomidine or clonidine (two alpha-2 adrenergic agonists) will improve the comfort of patients during spinal anesthesia for cesarean delivery. When added to standard spinal anesthesia consisting of bupivacaine (a local anesthetic) and fentanyl and morphine (two opioids), these medications may decrease some of the pulling/tugging/pressure sensations that patients sometimes feel during cesarean delivery, may prolong the anesthetic time, and may decrease postoperative pain.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (1 items) and avoid the listed exclusions (11 items).
Location: Columbia University Irving Medical Center/NewYork Presbyterian Hospital — New York, New York
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Significant cardiovascular, psychiatric or respiratory disease
- using opioids or with chronic pain syndrome
- Multiple gestation
- BMI \>40 kg/m2
- Quaternary or greater cesarean
- \< 37 weeks gestation
- Non-English or Spanish speaking
- planned vertical skin incision
- planned vertical (classical) uterine incision
- allergy to clonidine, dexmedetomidine or other study drug
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- Columbia University Irving Medical Center/NewYork Presbyterian Hospital — New York, New York
📞 Contact the Study Coordinator
Phone: (914) 584-9531
Email: rms7@cumc.columbia.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Cesarean Delivery
- Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous Therapies — Philadelphia, Pennsylvania
- Post-Operative Cesarean Section Cosmesis — Winston-Salem, North Carolina
- BUprenorphine Versus Morphine for Postcesarean Analgesia (BUMP) — New York, New York
- Duration of Urinary Catheterization Following Cesarean Deliveries Under Neuraxial Anesthesia — Vancouver, British Columbia
- IC-CS Risk: Patient Outcomes — Ann Arbor, Michigan
Explore by condition: All Cesarean Delivery clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.