Neurophysiological, Behavioral, and Cognitive Networks in Movement Disorders (NCT04061135)
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to investigate the brain activity associated with motor and non-motor symptoms of movement disorders, including Parkinson's disease (PD) and essential tremor. These movement disorders commonly have significant non-motor features, such as depression, cognitive and memory impairment, decreased attention, speech and language disturbances, and slower processing speeds. The investigators are interested in the brain activity associated with these motor and non-motor symptoms, and propose to investigate changes in brain activity while the investigators perform recordings of the surface and deep structures of the brain, in addition to the typical recordings the investigators perform, during routine deep brain stimulation (DBS) surgery.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (4 items) and avoid the listed exclusions (6 items).
Location: University of Alabama at Birmingham — Birmingham, Alabama
Age range: 18 Years
🧪 Interventions in This Study
- Response Inhibition and Deep Brain Stimulation in Parkinson's disease (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Inability to provide full and informed consent
- Are not surgical candidates due to co-morbid conditions or pregnancy
- Have not undergone an adequate trial of conservative medical management
- Have a clinical presentation for which DBS surgery is not indicated
- Are not able to participate in study-related activities
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- University of Alabama at Birmingham — Birmingham, Alabama
📞 Contact the Study Coordinator
Phone: (205) 975-0011
Email: jbentley@uabmc.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Movement Disorders
- Botulinum Toxin for the Treatment of Involuntary Movement Disorders — Bethesda, Maryland
- Neurophysiology of the Basal Ganglia, Thalamus, and Cerebellum in Patients With Movement Disorders — Philadelphia, Pennsylvania
- Towards Restoring Complex Movement After Paralysis: Algorithm Development With Healthy Participants — Los Angeles, California
- A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications — Baltimore, Maryland
- ExAblate Transcranial MRgFUS for the Management of Treatment-Refractory Movement Disorders — Toronto, Ontario
Explore by condition: All Movement Disorders clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.