Neurophysiology of the Basal Ganglia, Thalamus, and Cerebellum in Patients With Movement Disorders (NCT06848530)
🩺 Plain-English Summary (8th-Grade Level)
The research study is being conducted to better understand parts of the human brain called the cortex, basal ganglia, thalamus, and cerebellum in patients with movement disorders (such as Parkinson's disease, essential tremor, dystonia, or ataxia). These brain structures are involved in movement disorders. This study attempts to better understand the brain electrical activity associated with these disorders, both in patients with and without deep brain stimulation (DBS). Recordings are made from the scalp with a noninvasive electrode and/or through the DBS stimulator if the participant has a stimulator model that is able to sense brain activity. These recordings are analyzed along with measures of movement disorder symptoms to identify brain signal signatures of symptoms.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (7 items) and avoid the listed exclusions (1 items).
Location: Pennsylvania Hospital — Philadelphia, Pennsylvania
Age range: 18 Years
🧪 Interventions in This Study
- Prescribed Medications (OTHER)
- Deep brain stimulation adjustment (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria: \- Patients with dementia
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- Pennsylvania Hospital — Philadelphia, Pennsylvania
📞 Contact the Study Coordinator
Phone: (215) 746-4850
Email: Charlotte.Abeshaus@PennMedicine.upenn.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Movement Disorders
- Botulinum Toxin for the Treatment of Involuntary Movement Disorders — Bethesda, Maryland
- Neurophysiological, Behavioral, and Cognitive Networks in Movement Disorders — Birmingham, Alabama
- Towards Restoring Complex Movement After Paralysis: Algorithm Development With Healthy Participants — Los Angeles, California
- A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications — Baltimore, Maryland
- ExAblate Transcranial MRgFUS for the Management of Treatment-Refractory Movement Disorders — Toronto, Ontario
Explore by condition: All Movement Disorders clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.