Titration of Oxygen Levels During Mechanical Ventilation With Electronic Alerts (NCT04481581)
Titration of Inspired Oxygen During Mechanical Ventilation Using a Bedside Decision Support Tool
🩺 Plain-English Summary (8th-Grade Level)
Fractional oxygen during mechanical ventilation, is a life sustaining therapy in the intensive care unit , used for about a million patients annually. Oxygen therapy needs to be tightly balanced as both hypoxia and hyperoxia are harmful. Establishing precision in oxygenation has significant implications for improving patient outcomes, resource utilization and reducing iatrogenic harm to a vulnerable population. The investigators propose an approach using a oxygen titration protocol consisting of electronic health records based alerts to guide oxygen adjustment.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (1 items) and avoid the listed exclusions (7 items).
Location: Ohio State University Medical Center — Columbus, Ohio
Age range: 18 Years to 100 Years
🧪 Interventions in This Study
- Electronic Alerts (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Subjects without research authorization,
- Pregnancy,
- Pneumothorax,
- Carbon monoxide poisoning,
- Hyperbaric oxygen therapy
- Acute ST elevation Myocardial Infarction
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- Ohio State University Medical Center — Columbus, Ohio
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Mechanical Ventilation
- Optimizing Pain Treatment in Children On Mechanical Ventilation — Little Rock, Arkansas
- DIAPHRAGM STRENGTH AND LUNG VOLUMES — Toronto, Ontario
- Analgesia-First Sedation in Trauma Patients — Long Beach, California
- Ketamine Sedation in the ICU (KANINE) RCT — Hamilton, Ontario
- Prognostic Estimates Among ICU Clinicians — Chicago, Illinois
Explore by condition: All Mechanical Ventilation clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.