Analgesia-First Sedation in Trauma Patients (NCT05751863)
🩺 Plain-English Summary (8th-Grade Level)
The study's aim is to ascertain the best approach for providing sedation and pain management for patients who have sustained trauma and are requiring respiratory support from a mechanical ventilator. The common approach to patients who need mechanical ventilation is to provide continuous drips of sedatives and pain medicine and awaken the patient once a day to check the brain functions. Another approach is to provide pain medicine and reserve sedatives for only a short duration when needed. The difference between approaches has not been studied in Trauma patients.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (4 items) and avoid the listed exclusions (7 items).
Location: Long Beach Memorial Medical Center — Long Beach, California
Age range: 18 Years
🧪 Interventions in This Study
- Analgesia First Sedation Strategy for Mechanically Ventilated (MV) Trauma Subjects (OTHER)
- Protocol Directed Sedation and Daily Sedation Interruption (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Admission after resuscitation from cardiac arrest
- Significant neurological deficit due to a chronic disorder
- History of alcohol dependence and/or other illicit drug abuse
- Prior administration of continuous sedative/analgesic from a transferring institution
- Patient receiving neuromuscular blocking agents
- Allergy to midazolam, lorazepam, and/or propofol
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- Long Beach Memorial Medical Center — Long Beach, California
📞 Contact the Study Coordinator
Phone: 562-424-800
Email: tanios@memorialcare.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Mechanical Ventilation
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- DIAPHRAGM STRENGTH AND LUNG VOLUMES — Toronto, Ontario
- Ketamine Sedation in the ICU (KANINE) RCT — Hamilton, Ontario
- Prognostic Estimates Among ICU Clinicians — Chicago, Illinois
Explore by condition: All Mechanical Ventilation clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.