Who is eligible for clinical trial NCT04716803?

Participants must meet the protocol's inclusion criteria for Osteo Arthritis Knee. The stated age range is 45 Years to 75 Years. Confirm all requirements with the study coordinator.

Does clinical trial NCT04716803 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2022-01-24

Bone Marrow Aspirate Concentrate (BMAC)Treatment for Knee Osteoarthritis (NCT04716803)

🟢 Recruiting Observational / Diagnostic 💊 Investigational Drug / Biologic Sponsor: University of California, San Diego

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this study is to investigate the safety and effectiveness of bone marrow aspirate concentrate (BMAC) in patients with moderate to severe osteoarthritis of the knee. BMAC provides a rich source of mesenchymal stem cells (MSCs) and is a stem cell-based therapy that has been reported to preserve or improve the structure of joints. The Angel System is the device used in this study to concentrate bone marrow from the patient and is intended to separate a mixture of blood and bone marrow and collect plasma rich platelets preoperative to a surgical procedure. The goal of this study is to identify whether BMAC can be an effective and safe treatment for patients with osteoarthritis of the knee.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (4 items) and avoid the listed exclusions (1 items).

Location: University of California San Diego Koman Outpatient Pavilion — La Jolla, California

Age range: 45 Years to 75 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Kellgren Lawrence radiographic grade IV
Need for a total knee arthroscopy by the patients primary care provider/or orthopedist.
Persistent pain in target knee that is unresponsive to standard of care including acetametaphine, non-steroidal anti-inflammatory drugs, physical therapy and/or intraarticular corticosteroids and/or hyaluronic acid preparations.
Males or females aged 45-75.

Usually NOT eligible if any of the following apply:

Exclusion Criteria: \-

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

University of California San Diego Koman Outpatient Pavilion — La Jolla, California

📞 Contact the Study Coordinator

Phone: (858) 246-2381

Email: kkalunian@health.ucsd.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Osteo Arthritis Knee

SakuraBead Used as Resorbable Embolic for Genicular Artery Embolization — Birmingham, Alabama
The Role of Vitamin K on Knee Osteoarthritis Outcomes — Boston, Massachusetts
Safety and Tolerability of StroMel™ in Subjects with Moderate to Severe Osteoarthritis of the Knee Joint — Gaithersburg, Maryland
Radiographic Migration Analysis of the ATTUNE Cementless CR Fixed-Bearing Total Knee Replacement — Winnipeg, Manitoba
Effects of Vitamin K on Lower-extremity Function in Adults With Osteoarthritis: — Boston, Massachusetts

Explore by condition: All Osteo Arthritis Knee clinical trials

💡 How to Participate

Check the checklist above to see if you may qualify.
Contact the study coordinator using the phone/email above.
Ask about the visit schedule, what is covered at no cost, and any travel support.
Confirm with your own doctor before making a decision.

🏛️ View Official NIH Record ↗