Deep Brain Stimulation for Refractory Trigeminal Neuralgia with a Pontine Lesion (NCT05451251)
Deep Brain Stimulation for Refractory Trigeminal Neuralgia with a Pontine Lesion: a Pilot Study
🩺 Plain-English Summary (8th-Grade Level)
The aim of this study is to assess the feasibility of deep brain stimulation for refractory trigeminal neuralgia due to a pontine lesion, as is usually seen in the context of multiple sclerosis. These patients usually have severe intractable facial pain and current medical and surgical options generally fail to achieve long lasting pain relief. Hoping to improve pain control in this population, the investigators of this trial propose a novel technique consisting of implanting a deep brain stimulation lead within the pontine lesion to modulate the generation of pain signals.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (3 items) and avoid the listed exclusions (3 items).
Location: Centre Hospitalier Universitaire de Sherbrooke (CHUS) — Sherbrooke, Quebec
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Absolute contraindication to MRI
- Medical contraindication to the procedure
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- Centre Hospitalier Universitaire de Sherbrooke (CHUS) — Sherbrooke, Quebec
📞 Contact the Study Coordinator
Phone: (819) 346-1110
Email: Christian.Iorio-Morin@usherbrooke.ca
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Trigeminal Neuralgia
- Trigeminal Evoked Responses to Improve Rhizotomy — Minneapolis, Minnesota
- RP-008 in Combination With Daily Oral Varenicline for the Treatment of Trigeminal Neuralgia — Sherbrooke,
- MR Guided Focused Ultrasound (FUS) for the Treatment of Trigeminal Neuralgia — Baltimore, Maryland
- Emotion and Memory in Chronic Neuropathic Pain — Toronto, Ontario
- Post-Operative Trigeminal Pain After Microvascular Decompression for Trigeminal Neuralgia — Newark, New Jersey
Explore by condition: All Trigeminal Neuralgia clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.