Psychosis TMS Study (NCT05857137)
Investigational TMS Study of Cognitive Impairment in Early Psychosis
🩺 Plain-English Summary (8th-Grade Level)
The main goal of this study is to investigate the neural mechanisms of working memory function in patients with early psychosis using Transcranial Magnetic Stimulation (TMS) in conjunction with functional MRI. TMS is a noninvasive method used to modulate brain activity via changing magnetic fields applied over the surface of the scalp.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (2 items) and avoid the listed exclusions (5 items).
Location: Martinos Center for Biomedical Imaging — Charlestown, Massachusetts
Age range: 18 Years to 35 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- TMS incompatibility including metallic implants in head and neck, cardiac pacemakers, history of seizures, pregnancy.
- MRI-incompatibility including implanted aneurism clips, cardiac pacemakers, metal implants, intrauterine devices, tattoos containing metal ink, pregnancy, and claustrophobia
- Severe substance abuse within 3 months (nicotine allowed)
- Unstable medical or neurologic illness that would preclude participation in study procedures
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- Martinos Center for Biomedical Imaging — Charlestown, Massachusetts
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Psychosis
- Neurobehavioral Mechanisms of Social Isolation and Loneliness in Serious Mental Illness — Charlestown, Massachusetts
- Youth Nominated Support Team — Irvine, California
- Trajectories of Treatment Response as Window Into the Heterogeneity of Psychosis: a Longitudinal Multimodal Imaging Study — Birmingham, Alabama
- Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk — Glen Oaks, New York
- Cognitive Strategies in Early Psychosis 2 — Minneapolis, Minnesota
Explore by condition: All Psychosis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.