Evaluation of a Brief Computerized and Smart Phone-based Intervention for Stress in Regular Cannabis Users (NCT06085222)
Refinement and Testing of a Brief Computerized and Smart Phone-based Intervention for Stress in Regular Cannabis Users
🩺 Plain-English Summary (8th-Grade Level)
The prevalence of daily cannabis use and Cannabis Use Disorder (CUD) has increased in the United States over the past two decades. Brief, computerized harm reduction interventions that target specific high-risk CUD populations could be an efficient approach to reducing CUD. Distress intolerance , which refers to the tendency to negatively appraise and escape aversive emotional states, is a risk factor associated with stress-related cannabis use motivation and CUD severity/chronicity. Thus, a brief, accessible, low-cost intervention that reduces distress intolerance in those with CUD and elevated distress intolerance could have a significant public health impact. This proposed project aims to optimize an existing two-session computerized distress tolerance intervention and test its impact on distress intolerance and cannabis use outcomes in a randomized controlled trial. Specifically, the intervention will be condensed to one-session, its active ingredient bolstered, and augmented with smart phone-delivered therapy reminders. After obtaining feedback on the modified Emotional Engagement Distress Tolerance Intervention in a small sample, the intervention's efficacy compared to a stringent, credible, time-matched health education control intervention will be tested in a randomized controlled trial in 80 cannabis users with CUD and high distress intolerance. Distress intolerance, cannabis use, and psychosocial functioning outcomes will be evaluated. As an exploratory aim, a wristworn device will be used to measure objective stress responding in the real-world during the intervention period. Our central hypothesis is that, compared to a control intervention, the Emotional Engagement Distress Tolerance Intervention will produce superior reductions distress intolerance, stress-related cannabis use motivation, disordered cannabis use, and psychosocial functioning.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (8 items) and avoid the listed exclusions (9 items).
Location: The BRAINS Lab at Florida State University — Tallahassee, Florida
Age range: 18 Years to 30 Years
🧪 Interventions in This Study
- Emotional Engagement Distress Tolerance Intervention (BEHAVIORAL)
- Health Education Intervention (BEHAVIORAL)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Presence of acute/major psychiatric disturbance
- Current pregnancy
- Change in psychotropic medication within the past month
- Concurrently receiving treatment for cannabis use
- Concurrently receiving dialectical behavior therapy or exposure-based therapy for emotional disorders
- Planning to immediately quit using cannabis
- EEG contraindications
- Kidney disease
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- The BRAINS Lab at Florida State University — Tallahassee, Florida
📞 Contact the Study Coordinator
Phone: (850) 644-2445
Email: brains@psy.fsu.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Cannabis Use Disorder
- SV2A Density Cannabis Use Disorder — New Haven, Connecticut
- Cannabidiol and Cannabis Concentrate Users — Aurora, Colorado
- RS-tDCS for Cannabis Use Disorder: The C.A.R.E.S. Initiative — New York, New York
- A Brief Intervention for Cannabis Use — Charleston, South Carolina
- SCORE Emerging Adult Cannabis Use & Stress — Charleston, South Carolina
- Repetitive Transcranial Magnetic Stimulation for Cannabis Use Disorder — Toronto, Ontario
Explore by condition: All Cannabis Use Disorder clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.