🏛️ Verified NIH Record • Updated 2025-07-23

A Ketamine-assisted Group Therapy Intervention for Spanish-speaking Adults With Depression (NCT06597695)

🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic Sponsor: Juliana Zambrano, MD, MPH

🩺 Plain-English Summary (8th-Grade Level)

This is a pilot clinical trial to assess the feasibility, safety, and preliminary efficacy of ketamine-assisted group therapy for Spanish-speaking adults with depression

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (1 items) and avoid the listed exclusions (19 items).

Location: Massachusetts General Hospital, Chelsea — Chelsea, Massachusetts

Age range: 18 Years to 64 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Usually NOT eligible if any of the following apply:

  • Exclusion Criteria:
  • History of primary psychotic disorder, by history
  • History Bipolar I disorder, by history
  • Unstable complex PTSD, as assessed by study clinician
  • History of dissociative identity disorder
  • History of neurocognitive disorder
  • History of severe and/or recent substance use disorder, by history and as assessed by study clinician after clinical evaluation and interview
  • Uncontrolled hypertension, tachycardia, or unstable cardiopulmonary disease, by history a. Blood pressure on initial screen must be \<140/90 mmHg.
  • History of aortic dissection
  • History of myocardial infarction
  • History of aneurysm
  • History of hepatic impairment.

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

  • Massachusetts General Hospital, Chelsea — Chelsea, Massachusetts

📞 Contact the Study Coordinator

Phone: (617) 726-2000

Email: JZAMBRANO2@mgh.harvard.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Depression clinical trials

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗