39 Recruiting Studies Using Insulin

Active clinical trials that use this intervention, sourced directly from the NIH registry.

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Trials Using Insulin

🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Intranasal Insulin and Olanzapine Study in Healthy Volunteers

📍 University Health Network - Toronto General Hospital — Toronto, Ontario

Healthy Controls

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🔵 Active, Not Recruiting Phase2 / Phase3 💊 Investigational Drug / Biologic

Triple Therapy in T1DM

📍 Diabetes and Endocrinology Research Center of WNY — Williamsville, New York

Type 1 Diabetes Mellitus

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🔵 Active, Not Recruiting Observational / Diagnostic 💊 Investigational Drug / Biologic

Reprometabolic Syndrome Mediates Subfertility in Obesity

📍 University of Colorado Denver — Aurora, Colorado

Obesity

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🔵 Active, Not Recruiting Early Phase1 💊 Investigational Drug / Biologic

Role of NADPH Oxidase in Microvascular Dysfunction Following GDM

📍 University of Iowa — Iowa City, Iowa

Gestational Diabetes

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🔵 Active, Not Recruiting Phase4 💊 Investigational Drug / Biologic

Gestational Diabetes and Pharmacotherapy (GAP)

📍 Medical College of Wisconsin — Milwaukee, Wisconsin

Gestational Diabetes

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Frexalimab in Preservation of Endogenous Insulin Secretion Compared to Placebo in Adults, Adolescents and Children on Top of Insulin Therapy (FABULINUS)

📍 University of California San Francisco - Mission Bay- Site Number : 8400012 — San Francisco, California

Type 1 Diabetes Mellitus

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Liver Glycogen and Hypoglycemia in Humans

📍 University of Cincinnati — Cincinnati, Ohio

Hypoglycemia; Iatrogenic

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🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic

Effects of Modulators of Gluconeogenesis, Glycogenolysis and Glucokinase Activity

📍 Rita Basu — Birmingham, Alabama

Type 2 Diabetes

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🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

A Physiologic Analysis of Endoscopic Sleeve Gastroplasty (ESG)

📍 Brigham and Women's Hospital — Boston, Massachusetts

Non-alcoholic Steatohepatitis (NASH)

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🟡 Not Yet Recruiting Phase2 💊 Investigational Drug / Biologic

VITAL-IMPACT: Improving Cardiometabolic Health in Black Individuals Through Therapeutic Augmentation of Cyclic Guanosine Mono-Phosphate Signaling Pathway

📍 University of Alabama at Birmingham — Birmingham, Alabama

Cardiovascular Diseases

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🟡 Not Yet Recruiting Phase1 💊 Investigational Drug / Biologic

Human Models of Selective Insulin Resistance: Pancreatic Clamp

📍 Columbia University Irving Medical Center — New York, New York

Insulin Resistance

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🟡 Not Yet Recruiting Phase2 💊 Investigational Drug / Biologic

Restoring Vascular and Insulin Function To Augment Anti-Amyloid Therapy in Alzheimer's Disease

📍 Wake Forest Alzheimer's Disease Research Center (ADRC) Sticht Center for Healthy Aging — Winston-Salem, North Carolina

Alzheimer Disease

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🟡 Not Yet Recruiting Phase4 💊 Investigational Drug / Biologic

Sleep Loss and Circadian Misalignment - Mechanisms of Insulin Resistance

📍 Sleep and Performance Research Center — Spokane, Washington

Shift Work Schedule

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🟡 Not Yet Recruiting Phase2 💊 Investigational Drug / Biologic

Ketone Monitoring Approaches for Diabetic Ketoacidosis Risk Mitigation in People With T1D on Adjunctive SGLT-2 Inhibitors

📍 AdventHealth Translational Research Institute — Orlando, Florida

Type 1 Diabetes

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🟢 Recruiting Phase3 💊 Investigational Drug / Biologic

RCT Glargine vs NPH for Treatment of DM in Pregnancy

📍 Loyola University Medical Center — Maywood, Illinois

Diabetes Mellitus in Pregnancy

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🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

DETERMINE: Detemir vs NPH

📍 University of California, Los Angeles — Los Angeles, California

Gestational Diabetes

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🟢 Recruiting Observational / Diagnostic 💊 Investigational Drug / Biologic

Single vs Multi-Dose Insulin for Glycemic Control (SUGAR)

📍 Robert Wood Johnson Univeristy Hospital — New Brunswick, New Jersey

Diabetes in Pregnancy

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🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol

30 Day Insulin Balance Metabolic Health Optimization Protocol

📍 Efforia — New York, New York

Insulin

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🟢 Recruiting Phase4 💊 Investigational Drug / Biologic

Do Antipsychotics Block Insulin Action in the Brain: is it a Class Effect?

📍 Centre for Addiction and Mental Health — Toronto, Ontario

Brain Insulin Sensitivity

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🟢 Recruiting Observational / Diagnostic 💊 Investigational Drug / Biologic

Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes (START 2)

📍 University of Rochester Medical Center — Rochester, New York

Gestational Diabetes

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

Topical Insulin for Glaucoma

📍 Byers Eye Institute at Stanford University — Palo Alto, California

Glaucoma

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🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol

Inpatient Use of Personal Continuous Glucose Monitor (CGM) to Improve Diabetes Mellitus Control

📍 Mayo Clinic in Florida — Jacksonville, Florida

Diabetes Mellitus

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🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol

Genetic of Skeletal Muscle Insulin Resistance

📍 Texas Diabetes Institute - University Health System, San Antonio, Texas 78207 — San Antonio, Texas

Insulin Stimulated

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🟢 Recruiting Phase4 💊 Investigational Drug / Biologic

Modeling Ketosis-Prone Diabetes Remission Via Diverse Mechanisms of Glucotoxicity

📍 Grady Health System — Atlanta, Georgia

Ketosis Prone Diabetes

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🟢 Recruiting Phase4 💊 Investigational Drug / Biologic

Permissive Versus Strict Intrapartum Glucose Management in Type 1 Diabetes (PRISM-T1D)

📍 The Ohio State University Wexner Medical Center OB/GYN Maternal and Fetal Medicine — Columbus, Ohio

Pregnancy, High Risk

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🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research

Glycemic Variations During the Menstrual Cycle in Women With Type 1 Diabetes

📍 Institut de recherches cliniques de Montréal — Montreal, Quebec

Type1diabetes

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🟢 Recruiting Phase4 💊 Investigational Drug / Biologic

A Research Study to See How Well Weekly Insulin Icodec Maintains Blood Sugar Levels Compared to Daily Basal Insulins in Adults With Type 2 Diabetes

📍 Centricity Research Calgary Endocrinology — Calgary, Alberta

Diabetes Mellitus, Type 2

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🟢 Recruiting Early Phase1 💊 Investigational Drug / Biologic

Regional Lipolysis Insulin Regulation

📍 Mayo Clinic in Rochester — Rochester, Minnesota

Obesity

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

Effect of Insulin Lowering on Lipogenesis

📍 Columbia University Irving Medical Center — New York, New York

Hyperinsulinemia

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🟢 Recruiting Observational / Diagnostic 💊 Investigational Drug / Biologic

Effects of Antipsychotics on Brain Insulin Action in Females

📍 Centre for Addiction and Mental Health (CAMH) — Toronto, Ontario

Insulin Resistance

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🟢 Recruiting Observational / Diagnostic 💊 Investigational Drug / Biologic

Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes

📍 University of Rochester Medical Center — Rochester, New York

Gestational Diabetes

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🟢 Recruiting Phase4 💊 Investigational Drug / Biologic

GDM: Insulin with or Without Metformin?

📍 University of Virginia — Charlottesville, Virginia

Gestational Diabetes

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🟢 Recruiting Early Phase1 💊 Investigational Drug / Biologic

Gene Expression Changes In Young and Geriatric Skin

📍 Wright State Physicians — Fairborn, Ohio

UVB Phototherapy Burn

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🟢 Recruiting Early Phase1 💊 Investigational Drug / Biologic

Oxidative Stress in Microvascular Dysfunction Following Gestational Diabetes

📍 University of Iowa — Iowa City, Iowa

Gestational Diabetes

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🟢 Recruiting Phase4 💊 Investigational Drug / Biologic

Normal-weight Diabetes: Adipocyte-directed Therapy With Pioglitazone or Tirzepatide

📍 Stanford University — Palo Alto, California

Diabetes Mellitus, Type 2

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🟢 Recruiting Phase4 💊 Investigational Drug / Biologic

DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes

📍 University of Alabama — Tuscaloosa, Alabama

Gestational Diabetes Mellitus

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

Graded Insulin Suppression Test P&F

📍 Columbia University Irving Medical Center — New York, New York

Insulin Resistance

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🟢 Recruiting Early Phase1 💊 Investigational Drug / Biologic

Role of ET-1, Physical Activity, and Sedentary Behavior in Microvascular Dysfunction Following GDM

📍 University of Iowa — Iowa City, Iowa

Gestational Diabetes

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🟢 Recruiting Phase3 💊 Investigational Drug / Biologic

A Research Study to See How a Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine, Both in Combination With Insulin Aspart, in Adults With Type 1 Diabetes

📍 Cullman Clinical Trials — Cullman, Alabama

Diabetes Mellitus, Type 1

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